Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case report

<p>Abstract</p> <p>Introduction</p> <p>We report a case of tumor growth over a period of four decades, presenting with large multicentric lytic lesions of the skull and a profound mass effect, without neurological deficits. Clinical and radiological features of a patien...

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Main Authors: Krupp Wolfgang, Heckert Alexander, Holland Heidrun, Meixensberger Jürgen, Fritzsch Dominik
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Journal of Medical Case Reports
Online Access:http://www.jmedicalcasereports.com/content/6/1/85
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author Krupp Wolfgang
Heckert Alexander
Holland Heidrun
Meixensberger Jürgen
Fritzsch Dominik
author_facet Krupp Wolfgang
Heckert Alexander
Holland Heidrun
Meixensberger Jürgen
Fritzsch Dominik
author_sort Krupp Wolfgang
collection DOAJ
description <p>Abstract</p> <p>Introduction</p> <p>We report a case of tumor growth over a period of four decades, presenting with large multicentric lytic lesions of the skull and a profound mass effect, without neurological deficits. Clinical and radiological features of a patient with a giant intradiploic epidermoid and its impact on the choice of treatments are discussed.</p> <p>Case presentation</p> <p>An 81-year-old Caucasian man, who had first noticed a painless subcutaneous swelling over the left frontal scalp about 40 years ago, presented after a short episode of dizziness, which he experienced after treatment of focal retinal detachment. Computed tomography (CT) and magnetic resonance imaging (MRI) examinations revealed an exceptionally large tumor involving major parts of the skull with extensive destruction of the bone and distinct deformation of the brain. Considering his age and the absence of neurological deficits or pain, the patient refused the option of tumor removal and cranioplasty, yet agreed to a biopsy, which confirmed the suspected diagnosis.</p> <p>Conclusions</p> <p>The course of the disease demonstrates that even patients with large tumors, inducing distinct pathomorphological changes, do not necessarily experience significant impairment of their quality of life without surgery. This is an impressive example of the chance to lead a long and satisfying life without specific medical treatment, avoiding the inherent risks of these procedures. Yet, there is a clear indication for surgery of intradiploic epidermoids in most cases described in the literature.</p>
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spelling doaj.art-f4c220feb18e41379842adabdcb415c92022-12-22T02:47:13ZengBMCJournal of Medical Case Reports1752-19472012-03-01618510.1186/1752-1947-6-85Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case reportKrupp WolfgangHeckert AlexanderHolland HeidrunMeixensberger JürgenFritzsch Dominik<p>Abstract</p> <p>Introduction</p> <p>We report a case of tumor growth over a period of four decades, presenting with large multicentric lytic lesions of the skull and a profound mass effect, without neurological deficits. Clinical and radiological features of a patient with a giant intradiploic epidermoid and its impact on the choice of treatments are discussed.</p> <p>Case presentation</p> <p>An 81-year-old Caucasian man, who had first noticed a painless subcutaneous swelling over the left frontal scalp about 40 years ago, presented after a short episode of dizziness, which he experienced after treatment of focal retinal detachment. Computed tomography (CT) and magnetic resonance imaging (MRI) examinations revealed an exceptionally large tumor involving major parts of the skull with extensive destruction of the bone and distinct deformation of the brain. Considering his age and the absence of neurological deficits or pain, the patient refused the option of tumor removal and cranioplasty, yet agreed to a biopsy, which confirmed the suspected diagnosis.</p> <p>Conclusions</p> <p>The course of the disease demonstrates that even patients with large tumors, inducing distinct pathomorphological changes, do not necessarily experience significant impairment of their quality of life without surgery. This is an impressive example of the chance to lead a long and satisfying life without specific medical treatment, avoiding the inherent risks of these procedures. Yet, there is a clear indication for surgery of intradiploic epidermoids in most cases described in the literature.</p>http://www.jmedicalcasereports.com/content/6/1/85
spellingShingle Krupp Wolfgang
Heckert Alexander
Holland Heidrun
Meixensberger Jürgen
Fritzsch Dominik
Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case report
Journal of Medical Case Reports
title Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case report
title_full Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case report
title_fullStr Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case report
title_full_unstemmed Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case report
title_short Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case report
title_sort giant intradiploic epidermoid cyst with large osteolytic lesions of the skull a case report
url http://www.jmedicalcasereports.com/content/6/1/85
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