Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU Mortality
Abstract Introduction Cardiovascular collapse (CVC) is a serious complication of endotracheal intubation (ETI). Many studies have evaluated incidence and risk factors for postintubation hypotension. In this study, we considered postintubation CVC as systolic blood pressure ≤65 mm Hg recorded at leas...
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| Format: | Article |
| Language: | English |
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Springer
2020-08-01
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| Series: | Egyptian Journal of Critical Care Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1097/EJ9.0000000000000008 |
| _version_ | 1826560331675074560 |
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| author | Amr Mohamed Elsharkawy Samir Mohammed Al-Awady Tamer Abdullah Helmy |
| author_facet | Amr Mohamed Elsharkawy Samir Mohammed Al-Awady Tamer Abdullah Helmy |
| author_sort | Amr Mohamed Elsharkawy |
| collection | DOAJ |
| description | Abstract Introduction Cardiovascular collapse (CVC) is a serious complication of endotracheal intubation (ETI). Many studies have evaluated incidence and risk factors for postintubation hypotension. In this study, we considered postintubation CVC as systolic blood pressure ≤65 mm Hg recorded at least once and/or ≤90 mm Hg for ≥30 minutes or the requirement of vasopressors and/or inotropes. The aim of this study is to assess the incidence and potential risk factor for severe CVC after ETI and its impact on intensive care unit (ICU) length of stay and mortality. Materials and Methods This is a prospective cohort study that was conducted on 300 patients who were classified into two categories: those who were hemodynamically stable after intubation and those who collapsed. Different variables were documented in both groups and compared with the incidence of postintubation CVC. ICU length of stay and 28-day mortality were assessed in both groups. Results 26.3% of subjects have developed CVC after ETI. Factors that were associated with increased incidence of CVC include old age, heart failure, chronic kidney disease, COPD, higher heart rate before and during intubation, and propofol usage for intubation. Postintubation CVC had a statistically significant association with prolonged ICU length of stay and increased ICU mortality. Conclusion Postintubation CVC is associated with poorer outcomes with regard to ICU length of stay and ICU mortality. There are potential risk factors that need further evaluation to predict and/or decrease the incidence of CVC after ETI. |
| first_indexed | 2025-03-14T09:14:35Z |
| format | Article |
| id | doaj.art-f4c25d5a72be45f5974edaaf638e09f1 |
| institution | Directory Open Access Journal |
| issn | 2090-7303 2090-9209 |
| language | English |
| last_indexed | 2025-03-14T09:14:35Z |
| publishDate | 2020-08-01 |
| publisher | Springer |
| record_format | Article |
| series | Egyptian Journal of Critical Care Medicine |
| spelling | doaj.art-f4c25d5a72be45f5974edaaf638e09f12025-03-02T12:17:36ZengSpringerEgyptian Journal of Critical Care Medicine2090-73032090-92092020-08-0171263210.1097/EJ9.0000000000000008Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU MortalityAmr Mohamed Elsharkawy0Samir Mohammed Al-Awady1Tamer Abdullah Helmy2Critical Care Medicine department, Alexandria UniversityCritical Care Medicine department, Alexandria UniversityCritical Care Medicine department, Alexandria UniversityAbstract Introduction Cardiovascular collapse (CVC) is a serious complication of endotracheal intubation (ETI). Many studies have evaluated incidence and risk factors for postintubation hypotension. In this study, we considered postintubation CVC as systolic blood pressure ≤65 mm Hg recorded at least once and/or ≤90 mm Hg for ≥30 minutes or the requirement of vasopressors and/or inotropes. The aim of this study is to assess the incidence and potential risk factor for severe CVC after ETI and its impact on intensive care unit (ICU) length of stay and mortality. Materials and Methods This is a prospective cohort study that was conducted on 300 patients who were classified into two categories: those who were hemodynamically stable after intubation and those who collapsed. Different variables were documented in both groups and compared with the incidence of postintubation CVC. ICU length of stay and 28-day mortality were assessed in both groups. Results 26.3% of subjects have developed CVC after ETI. Factors that were associated with increased incidence of CVC include old age, heart failure, chronic kidney disease, COPD, higher heart rate before and during intubation, and propofol usage for intubation. Postintubation CVC had a statistically significant association with prolonged ICU length of stay and increased ICU mortality. Conclusion Postintubation CVC is associated with poorer outcomes with regard to ICU length of stay and ICU mortality. There are potential risk factors that need further evaluation to predict and/or decrease the incidence of CVC after ETI.https://doi.org/10.1097/EJ9.0000000000000008collapseendotracheal intubationpostintubation hypotension |
| spellingShingle | Amr Mohamed Elsharkawy Samir Mohammed Al-Awady Tamer Abdullah Helmy Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU Mortality Egyptian Journal of Critical Care Medicine collapse endotracheal intubation postintubation hypotension |
| title | Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU Mortality |
| title_full | Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU Mortality |
| title_fullStr | Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU Mortality |
| title_full_unstemmed | Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU Mortality |
| title_short | Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU Mortality |
| title_sort | postintubation hypotension and its association with prolonged icu length of stay and icu mortality |
| topic | collapse endotracheal intubation postintubation hypotension |
| url | https://doi.org/10.1097/EJ9.0000000000000008 |
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