Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scars
Objective To evaluate the efficacy and safety of trephine resection combined with fractional ablative CO2 laser for pitted acne scars. Methods Sixty eight patients with facial pitted acne scars were enrolled from the Medical Cosmetology Center of Zhengzhou People's Hospital from February 2019 t...
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| Format: | Article |
| Language: | zho |
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editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2023-12-01
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| Series: | Pifu-xingbing zhenliaoxue zazhi |
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| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.06.006 |
| _version_ | 1827311962425393152 |
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| author | Yanhong ZHANG Yucheng HUANG Hui XU Xiaoyu CHEN Yimeng LIU Xiaopan FAN Linlin SUN |
| author_facet | Yanhong ZHANG Yucheng HUANG Hui XU Xiaoyu CHEN Yimeng LIU Xiaopan FAN Linlin SUN |
| author_sort | Yanhong ZHANG |
| collection | DOAJ |
| description | Objective To evaluate the efficacy and safety of trephine resection combined with fractional ablative CO2 laser for pitted acne scars. Methods Sixty eight patients with facial pitted acne scars were enrolled from the Medical Cosmetology Center of Zhengzhou People's Hospital from February 2019 to February 2022. The patients were randomly divided into the observation (30 patients) and the control groups (38 patients). The observation group was treated with trephine resection combined with CO2 laser, and the control group was treated with fractional ablative CO2 laser alone. The efficacy and the ECCA scale (Echelle d 'Evaluation Clinique des Cicatrices d 'acne) were compared between the two groups after 6-month treatment. Results Before the treatment, ECCA scores were comparable between the observation and the control groups [50.00 (43.75, 60.00) vs. 47.50 (37.50, 60.00), P=0.535]. After 6-month treatment, the ECCA scores in both groups were significantly lower than the baseline (both P<0.01), and the ECCA scores were significantly lower in the observation group [20.00 (15.00, 30.00)] than in the controls [25.00 (20.00, 30.00)] (P=0.032). The effective rate in the observation group was significantly higher than that in the controls (93.33% vs. 71.05%, P=0.020). But adverse reactions did not differ significantly between the two groups(P=1.000). Conclusions Trephine resection combined with fractional ablative CO2 laser is more effective than fractional ablative CO2 laser alone for facial pitted acne scars and is safe. |
| first_indexed | 2024-04-24T20:29:47Z |
| format | Article |
| id | doaj.art-f4c3b19317ef438196cb62353b04ccdd |
| institution | Directory Open Access Journal |
| issn | 1674-8468 |
| language | zho |
| last_indexed | 2024-04-24T20:29:47Z |
| publishDate | 2023-12-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj.art-f4c3b19317ef438196cb62353b04ccdd2024-03-22T02:46:48Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682023-12-0130651852310.3969/j.issn.1674-8468.2023.06.006Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scarsYanhong ZHANG0Yucheng HUANG1Hui XU2Xiaoyu CHEN3Yimeng LIU4Xiaopan FAN5Linlin SUN6Fifth Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou People's Hospital, Zhengzhou 450000, ChinaFifth Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou People's Hospital, Zhengzhou 450000, ChinaFifth Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou People's Hospital, Zhengzhou 450000, ChinaFifth Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou People's Hospital, Zhengzhou 450000, ChinaFifth Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou People's Hospital, Zhengzhou 450000, ChinaFifth Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou People's Hospital, Zhengzhou 450000, ChinaZhengzhou No.7 People's Hospital, Zhengzhou 450006, ChinaObjective To evaluate the efficacy and safety of trephine resection combined with fractional ablative CO2 laser for pitted acne scars. Methods Sixty eight patients with facial pitted acne scars were enrolled from the Medical Cosmetology Center of Zhengzhou People's Hospital from February 2019 to February 2022. The patients were randomly divided into the observation (30 patients) and the control groups (38 patients). The observation group was treated with trephine resection combined with CO2 laser, and the control group was treated with fractional ablative CO2 laser alone. The efficacy and the ECCA scale (Echelle d 'Evaluation Clinique des Cicatrices d 'acne) were compared between the two groups after 6-month treatment. Results Before the treatment, ECCA scores were comparable between the observation and the control groups [50.00 (43.75, 60.00) vs. 47.50 (37.50, 60.00), P=0.535]. After 6-month treatment, the ECCA scores in both groups were significantly lower than the baseline (both P<0.01), and the ECCA scores were significantly lower in the observation group [20.00 (15.00, 30.00)] than in the controls [25.00 (20.00, 30.00)] (P=0.032). The effective rate in the observation group was significantly higher than that in the controls (93.33% vs. 71.05%, P=0.020). But adverse reactions did not differ significantly between the two groups(P=1.000). Conclusions Trephine resection combined with fractional ablative CO2 laser is more effective than fractional ablative CO2 laser alone for facial pitted acne scars and is safe.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.06.006trephine resectionfractional ablative laserpitted acne scaracne |
| spellingShingle | Yanhong ZHANG Yucheng HUANG Hui XU Xiaoyu CHEN Yimeng LIU Xiaopan FAN Linlin SUN Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scars Pifu-xingbing zhenliaoxue zazhi trephine resection fractional ablative laser pitted acne scar acne |
| title | Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scars |
| title_full | Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scars |
| title_fullStr | Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scars |
| title_full_unstemmed | Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scars |
| title_short | Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scars |
| title_sort | therapeutic effect of trephine resection combined with fractional ablative co2 laser in the treatment of pitted acne scars |
| topic | trephine resection fractional ablative laser pitted acne scar acne |
| url | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2023.06.006 |
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