Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia.
The study investigates long-term recognition memory in congenital prosopagnosia (CP), a lifelong impairment in face identification that is present from birth. Previous investigations of processing deficits in CP have mostly relied on short-term recognition tests to estimate the scope and severity of...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2011-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3026793?pdf=render |
| _version_ | 1819123914614243328 |
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| author | Rainer Stollhoff Jürgen Jost Tobias Elze Ingo Kennerknecht |
| author_facet | Rainer Stollhoff Jürgen Jost Tobias Elze Ingo Kennerknecht |
| author_sort | Rainer Stollhoff |
| collection | DOAJ |
| description | The study investigates long-term recognition memory in congenital prosopagnosia (CP), a lifelong impairment in face identification that is present from birth. Previous investigations of processing deficits in CP have mostly relied on short-term recognition tests to estimate the scope and severity of individual deficits. We firstly report on a controlled test of long-term (one year) recognition memory for faces and objects conducted with a large group of participants with CP. Long-term recognition memory is significantly impaired in eight CP participants (CPs). In all but one case, this deficit was selective to faces and didn't extend to intra-class recognition of object stimuli. In a test of famous face recognition, long-term recognition deficits were less pronounced, even after accounting for differences in media consumption between controls and CPs. Secondly, we combined test results on long-term and short-term recognition of faces and objects, and found a large heterogeneity in severity and scope of individual deficits. Analysis of the observed heterogeneity revealed a dissociation of CP into subtypes with a homogeneous phenotypical profile. Thirdly, we found that among CPs self-assessment of real-life difficulties, based on a standardized questionnaire, and experimentally assessed face recognition deficits are strongly correlated. Our results demonstrate that controlled tests of long-term recognition memory are needed to fully assess face recognition deficits in CP. Based on controlled and comprehensive experimental testing, CP can be dissociated into subtypes with a homogeneous phenotypical profile. The CP subtypes identified align with those found in prosopagnosia caused by cortical lesions; they can be interpreted with respect to a hierarchical neural system for face perception. |
| first_indexed | 2024-12-22T07:15:55Z |
| format | Article |
| id | doaj.art-f4c3f1c4df0a4013ac158a31fa28434d |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T07:15:55Z |
| publishDate | 2011-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-f4c3f1c4df0a4013ac158a31fa28434d2022-12-21T18:34:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032011-01-0161e1570210.1371/journal.pone.0015702Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia.Rainer StollhoffJürgen JostTobias ElzeIngo KennerknechtThe study investigates long-term recognition memory in congenital prosopagnosia (CP), a lifelong impairment in face identification that is present from birth. Previous investigations of processing deficits in CP have mostly relied on short-term recognition tests to estimate the scope and severity of individual deficits. We firstly report on a controlled test of long-term (one year) recognition memory for faces and objects conducted with a large group of participants with CP. Long-term recognition memory is significantly impaired in eight CP participants (CPs). In all but one case, this deficit was selective to faces and didn't extend to intra-class recognition of object stimuli. In a test of famous face recognition, long-term recognition deficits were less pronounced, even after accounting for differences in media consumption between controls and CPs. Secondly, we combined test results on long-term and short-term recognition of faces and objects, and found a large heterogeneity in severity and scope of individual deficits. Analysis of the observed heterogeneity revealed a dissociation of CP into subtypes with a homogeneous phenotypical profile. Thirdly, we found that among CPs self-assessment of real-life difficulties, based on a standardized questionnaire, and experimentally assessed face recognition deficits are strongly correlated. Our results demonstrate that controlled tests of long-term recognition memory are needed to fully assess face recognition deficits in CP. Based on controlled and comprehensive experimental testing, CP can be dissociated into subtypes with a homogeneous phenotypical profile. The CP subtypes identified align with those found in prosopagnosia caused by cortical lesions; they can be interpreted with respect to a hierarchical neural system for face perception.http://europepmc.org/articles/PMC3026793?pdf=render |
| spellingShingle | Rainer Stollhoff Jürgen Jost Tobias Elze Ingo Kennerknecht Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia. PLoS ONE |
| title | Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia. |
| title_full | Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia. |
| title_fullStr | Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia. |
| title_full_unstemmed | Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia. |
| title_short | Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia. |
| title_sort | deficits in long term recognition memory reveal dissociated subtypes in congenital prosopagnosia |
| url | http://europepmc.org/articles/PMC3026793?pdf=render |
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