Many Activities, One Structure: Functional Plasticity of Ribozyme Folds

Many Activities, One Structure: Functional Plasticity of Ribozyme Folds

Catalytic RNAs, or ribozymes, are involved in a number of essential biological processes, such as replication of RNA genomes and mobile genetic elements, RNA splicing, translation, and RNA degradation. The function of ribozymes requires the formation of active sites decorated with RNA functional gro...

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Bibliographic Details
Main Authors: Matthew W.L. Lau, Adrian R. Ferré-D’Amaré
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
ribozyme
in vitro selection
fitness landscape
Online Access:http://www.mdpi.com/1420-3049/21/11/1570

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