The modulation of platelet function by growth hormone in growth hormone deficient Hypopituitary patients

The modulation of platelet function by growth hormone in growth hormone deficient Hypopituitary patients

Abstract Background Growth hormone deficiency (GHD) has been implicated in increased cardiovascular and cerebrovascular disease risk seen in hypopituitarism, however the mechanism remains speculative. We hypothesise that platelet abnormalities may play a contributory role. Herein we examined platele...

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Bibliographic Details
Main Authors: Irene K Oglesby, David Slattery, Nigel Glynn, Saket Gupta, Karen Duggan, Martin Cuesta, Eimear Dunne, Aoife Garrahy, Siobhan Toner, Dermot Kenny, Amar Agha
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Endocrine Disorders
Subjects:
Hypopituitarism
Growth hormone
Platelets
von Willebrand factor
Thrombosis
Platelet-vWF interaction
Online Access:https://doi.org/10.1186/s12902-023-01448-6

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