FTO facilitates cancer metastasis by modifying the m6A level of FAP to induce integrin/FAK signaling in non-small cell lung cancer

FTO facilitates cancer metastasis by modifying the m6A level of FAP to induce integrin/FAK signaling in non-small cell lung cancer

Abstract Background Emerging evidence suggests the critical roles of N6-methyladenosine (m6A) RNA modification in tumorigenesis and tumor progression. However, the role of m6A in non-small cell lung cancer (NSCLC) is still unclear. This study aimed to explore the role of the m6A demethylase fat mass...

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Bibliographic Details
Main Authors: Lirong Gao, Anqi Wang, Yuling Chen, Xin Cai, Yue Li, Jian Zhao, Yang Zhang, Weijie Zhang, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu, Jian-an Huang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cell Communication and Signaling
Subjects:
N6-methyladenosine (m6A)
Fat mass and obesity-associated protein (FTO)
Fibroblast activation protein (FAP)
Carcinoma
Non-Small-Cell Lung (NSCLC)
Metastasis
Online Access:https://doi.org/10.1186/s12964-023-01343-6

Internet

https://doi.org/10.1186/s12964-023-01343-6

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