“Bisphenol a: an emerging threat to male fertility”
Abstract Background Among the factors causing male infertility, one of the most debated is the exposure to environmental contaminants. Recently, the chemical compound Bisphenol A (BPA) has drawn attention from the reproductive science community, due to its ubiquitous presence in day-to-day life. Its...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-01-01
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| Series: | Reproductive Biology and Endocrinology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12958-018-0447-6 |
| _version_ | 1819032901439717376 |
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| author | Federica Cariati Nadja D’Uonno Francesca Borrillo Stefania Iervolino Giacomo Galdiero Rossella Tomaiuolo |
| author_facet | Federica Cariati Nadja D’Uonno Francesca Borrillo Stefania Iervolino Giacomo Galdiero Rossella Tomaiuolo |
| author_sort | Federica Cariati |
| collection | DOAJ |
| description | Abstract Background Among the factors causing male infertility, one of the most debated is the exposure to environmental contaminants. Recently, the chemical compound Bisphenol A (BPA) has drawn attention from the reproductive science community, due to its ubiquitous presence in day-to-day life. Its toxic action appears to mainly affect the male reproductive system, directly impacting male fertility. Main The purpose of this review is to investigate current research data on BPA, providing an overview of the findings obtained from studies in animal and human models, as well as on its supposed mechanisms of action. Conclusion A clear understanding of BPA action mechanisms, as well as the presumed risks deriving from its exposure, is becoming crucial to preserve male fertility. The development and validation of methodologies to detect BPA toxic effects on reproductive organs can provide greater awareness of the potential threat that this chemical represents. |
| first_indexed | 2024-12-21T07:09:18Z |
| format | Article |
| id | doaj.art-f4e42e31c2074227be0ca3ecb321ca37 |
| institution | Directory Open Access Journal |
| issn | 1477-7827 |
| language | English |
| last_indexed | 2024-12-21T07:09:18Z |
| publishDate | 2019-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Reproductive Biology and Endocrinology |
| spelling | doaj.art-f4e42e31c2074227be0ca3ecb321ca372022-12-21T19:12:00ZengBMCReproductive Biology and Endocrinology1477-78272019-01-011711810.1186/s12958-018-0447-6“Bisphenol a: an emerging threat to male fertility”Federica Cariati0Nadja D’Uonno1Francesca Borrillo2Stefania Iervolino3Giacomo Galdiero4Rossella Tomaiuolo5Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico IICEINGE-Biotecnologie Avanzate s.c.a r.l.Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico IIKronosDNA s.r.l., Spin-off Università degli Studi di Napoli Federico IIDipartimento di Medicina Clinica e Chirurgia, Università degli Studi di Napoli Federico IIDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico IIAbstract Background Among the factors causing male infertility, one of the most debated is the exposure to environmental contaminants. Recently, the chemical compound Bisphenol A (BPA) has drawn attention from the reproductive science community, due to its ubiquitous presence in day-to-day life. Its toxic action appears to mainly affect the male reproductive system, directly impacting male fertility. Main The purpose of this review is to investigate current research data on BPA, providing an overview of the findings obtained from studies in animal and human models, as well as on its supposed mechanisms of action. Conclusion A clear understanding of BPA action mechanisms, as well as the presumed risks deriving from its exposure, is becoming crucial to preserve male fertility. The development and validation of methodologies to detect BPA toxic effects on reproductive organs can provide greater awareness of the potential threat that this chemical represents.http://link.springer.com/article/10.1186/s12958-018-0447-6Bisphenol aMale fertilityEndocrine disrupting compounds |
| spellingShingle | Federica Cariati Nadja D’Uonno Francesca Borrillo Stefania Iervolino Giacomo Galdiero Rossella Tomaiuolo “Bisphenol a: an emerging threat to male fertility” Reproductive Biology and Endocrinology Bisphenol a Male fertility Endocrine disrupting compounds |
| title | “Bisphenol a: an emerging threat to male fertility” |
| title_full | “Bisphenol a: an emerging threat to male fertility” |
| title_fullStr | “Bisphenol a: an emerging threat to male fertility” |
| title_full_unstemmed | “Bisphenol a: an emerging threat to male fertility” |
| title_short | “Bisphenol a: an emerging threat to male fertility” |
| title_sort | bisphenol a an emerging threat to male fertility |
| topic | Bisphenol a Male fertility Endocrine disrupting compounds |
| url | http://link.springer.com/article/10.1186/s12958-018-0447-6 |
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