Proteogenomic characterization of primary colorectal cancer and metastatic progression identifies proteome-based subtypes and signatures

Proteogenomic characterization of primary colorectal cancer and metastatic progression identifies proteome-based subtypes and signatures

Summary: Metastatic progression of colorectal adenocarcinoma (CRC) remains poorly understood and poses significant challenges for treatment. To overcome these challenges, we performed multiomics analyses of primary CRC and liver metastases. Genomic alterations, such as structural variants or copy nu...

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Bibliographic Details
Main Authors: Atsushi Tanaka, Makiko Ogawa, Yihua Zhou, Kei Namba, Ronald C. Hendrickson, Matthew M. Miele, Zhuoning Li, David S. Klimstra, Patrick G. Buckley, Jeffrey Gulcher, Julia Y. Wang, Michael H.A. Roehrl
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724001384

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