Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis
The purpose of this study was to identify risk factors and improve preventive strategies for febrile neutropenia (FEN) in children with leukemia who were receiving ciprofloxacin prophylaxis. The study included 100 children with leukemia [n=80 with acute lymphoblastic leukemia and n=20 with acute mye...
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Format: | Article |
Language: | English |
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Galenos Publishing House
2023-08-01
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Series: | Turkish Journal of Hematology |
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Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-73444 |
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author | Zühre Kaya Nurettin Alıcı Serap Kırkız Ülker Koçak |
author_facet | Zühre Kaya Nurettin Alıcı Serap Kırkız Ülker Koçak |
author_sort | Zühre Kaya |
collection | DOAJ |
description | The purpose of this study was to identify risk factors and improve preventive strategies for febrile neutropenia (FEN) in children with leukemia who were receiving ciprofloxacin prophylaxis. The study included 100 children with leukemia [n=80 with acute lymphoblastic leukemia and n=20 with acute myeloblastic leukemia (AML)]. Patients were divided into two groups based on whether they had three or fewer FEN episodes (Group 1) or more than three FEN episodes (Group 2). Group 1 contained 63 (63%) of the 100 patients, while Group 2 contained 37 (37%). Older age (≥7 years), leukemia type, prolonged neutropenia (>10 days), and the presence of neutropenia and hypogammaglobulinemia at diagnosis were all risk factors for having more than three FEN episodes. Our findings suggest that, in addition to ciprofloxacin prophylaxis, identifying risk factors and improving preventive strategies could help reduce FEN episodes in children with leukemia. |
first_indexed | 2024-03-12T11:26:46Z |
format | Article |
id | doaj.art-f4e894ff81c04597b67c48e64b49cf35 |
institution | Directory Open Access Journal |
issn | 1308-5263 |
language | English |
last_indexed | 2024-03-12T11:26:46Z |
publishDate | 2023-08-01 |
publisher | Galenos Publishing House |
record_format | Article |
series | Turkish Journal of Hematology |
spelling | doaj.art-f4e894ff81c04597b67c48e64b49cf352023-09-01T08:46:20ZengGalenos Publishing HouseTurkish Journal of Hematology1308-52632023-08-0140318318610.4274/tjh.galenos.2023.2023-0116TJH-73444Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin ProphylaxisZühre Kaya0Nurettin Alıcı1Serap Kırkız2Ülker Koçak3Gazi University Faculty of Medicine, Department of Pediatric Hematology, Ankara, TürkiyeGazi University Faculty of Medicine, Department of Pediatric Hematology, Ankara, TürkiyeGazi University Faculty of Medicine, Department of Pediatric Hematology, Ankara, TürkiyeGazi University Faculty of Medicine, Department of Pediatric Hematology, Ankara, TürkiyeThe purpose of this study was to identify risk factors and improve preventive strategies for febrile neutropenia (FEN) in children with leukemia who were receiving ciprofloxacin prophylaxis. The study included 100 children with leukemia [n=80 with acute lymphoblastic leukemia and n=20 with acute myeloblastic leukemia (AML)]. Patients were divided into two groups based on whether they had three or fewer FEN episodes (Group 1) or more than three FEN episodes (Group 2). Group 1 contained 63 (63%) of the 100 patients, while Group 2 contained 37 (37%). Older age (≥7 years), leukemia type, prolonged neutropenia (>10 days), and the presence of neutropenia and hypogammaglobulinemia at diagnosis were all risk factors for having more than three FEN episodes. Our findings suggest that, in addition to ciprofloxacin prophylaxis, identifying risk factors and improving preventive strategies could help reduce FEN episodes in children with leukemia.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-73444febrile neutropeniachildrenleukemiarisk factorprophylaxis |
spellingShingle | Zühre Kaya Nurettin Alıcı Serap Kırkız Ülker Koçak Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis Turkish Journal of Hematology febrile neutropenia children leukemia risk factor prophylaxis |
title | Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis |
title_full | Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis |
title_fullStr | Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis |
title_full_unstemmed | Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis |
title_short | Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis |
title_sort | identifying risk factors and improving preventive strategies for febrile neutropenia in children with leukemia receiving ciprofloxacin prophylaxis |
topic | febrile neutropenia children leukemia risk factor prophylaxis |
url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-73444 |
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