Comprehensive bulk and single-cell transcriptome profiling give useful insights into the characteristics of osteoarthritis associated synovial macrophages

BackgroundOsteoarthritis (OA) is a common chronic joint disease, but the association between molecular and cellular events and the pathogenic process of OA remains unclear.ObjectiveThe study aimed to identify key molecular and cellular events in the processes of immune infiltration of the synovium i...

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Bibliographic Details
Main Authors: Shengyou Liao, Ming Yang, Dandan Li, Ye Wu, Hong Sun, Jingxiao Lu, Xinying Liu, Tingting Deng, Yujie Wang, Ni Xie, Donge Tang, Guohui Nie, Xiaoqin Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1078414/full