Effects of TCF7L2 rs7903146 variant on metformin response in patients with type 2 diabetes

Effects of TCF7L2 rs7903146 variant on metformin response in patients with type 2 diabetes

The response to metformin, the most commonly used drug for the treatment of type 2 diabetes (T2D), is highly variable. The common variant rs7903146 C>T within the transcription factor 7-like 2 gene (TCF7L2) is the strongest genetic risk factor associated with T2D to date. In this study, we explo...

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Bibliographic Details
Main Authors:	Tanja Dujic, Tamer Bego, Maja Malenica, Zelija Velija-Asimi, Emma Ahlqvist, Leif Groop, Ewan R. Pearson, Adlija Causevic, Sabina Semiz
Format:	Article
Language:	English
Published:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2019-11-01
Series:	Biomolecules & Biomedicine
Subjects:	Metformin type 2 diabetes pharmacogenetics transcription factor 7-like 2 gene TCF7L2
Online Access:	https://www.bjbms.org/ojs/index.php/bjbms/article/view/4181

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