Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide Polymorphisms
In Senegal, sheep breeds have adapted to their environment and play a key socio-economic role. This study aimed to explore the genetic diversity and structure of four Senegalese sheep breeds (Peul-peul, Djallonke, Touabire, and Ladoum) and their relationships with global sheep breeds. To that end, f...
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MDPI AG
2022-06-01
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| author | Ayao Missohou Basse Kaboré Laurence Flori Simplice Bosco Ayssiwede Jean-Luc Hornick Marianne Raes Jean-François Cabaraux |
| author_facet | Ayao Missohou Basse Kaboré Laurence Flori Simplice Bosco Ayssiwede Jean-Luc Hornick Marianne Raes Jean-François Cabaraux |
| author_sort | Ayao Missohou |
| collection | DOAJ |
| description | In Senegal, sheep breeds have adapted to their environment and play a key socio-economic role. This study aimed to explore the genetic diversity and structure of four Senegalese sheep breeds (Peul-peul, Djallonke, Touabire, and Ladoum) and their relationships with global sheep breeds. To that end, forty-seven sheep were genotyped using the OvineSNP50 BeadChip, and these genotypic data were analysed with those of 73 sheep breeds representative of worldwide ovine diversity (2729 animals). The average observed heterozygosity (Ho) ranged from 0.293 in Djallonke sheep to 0.339 in Touabire sheep. The estimated Fis values were low, ranging from 0.019 for Ladoum to 0.034 for Peul-peul sheep. The estimated Fst values were low (0.003–0.044) among the trypanosusceptible breeds (Peul-peul, Touabire, and Ladoum) but high between the previous breeds and the trypanotolerant Djallonke breed (0.075–0.116), indicating better genetic conservation of the Djallonke sheep. A principal component analysis revealed clustering of the Senegalese sheep breeds according to their geographic distribution. However, owing to genetic improvement practices, the introgression of Touabire sheep blood seems to have reshaped the genetic landscape of the trypanosusceptible sheep breeds in Senegal. The Senegalese sheep breeds showed lower genetic diversity than their presumed ancestral sheep breeds of the Middle East. They also presented some relatedness with Caribbean sheep breeds, which reveals their contribution to the global genetic diversity and to the development of Caribbean sheep breeds. |
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| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T00:37:46Z |
| publishDate | 2022-06-01 |
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| series | Animals |
| spelling | doaj.art-f4f291b72c494fdd8e2210028787a26e2023-11-23T15:14:20ZengMDPI AGAnimals2076-26152022-06-011212151210.3390/ani12121512Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide PolymorphismsAyao Missohou0Basse Kaboré1Laurence Flori2Simplice Bosco Ayssiwede3Jean-Luc Hornick4Marianne Raes5Jean-François Cabaraux6Animal Production and Nutrition Unit, Inter-State School of Veterinary Science and Medicine (EISMV), Dakar BP 577, SenegalAnimal Production and Nutrition Unit, Inter-State School of Veterinary Science and Medicine (EISMV), Dakar BP 577, SenegalSELMET, INRAE, CIRAD, L’Institut Agro, University of Montpellier, 34000 Montpellier, FranceAnimal Production and Nutrition Unit, Inter-State School of Veterinary Science and Medicine (EISMV), Dakar BP 577, SenegalDepartment of Veterinary Management of Animal Resources, FARAH, Faculty of Veterinary Medicine, University of Liège, 4000 Liège, BelgiumDepartment of Veterinary Medicine, URVI, University of Namur, 5000 Namur, BelgiumDepartment of Veterinary Management of Animal Resources, FARAH, Faculty of Veterinary Medicine, University of Liège, 4000 Liège, BelgiumIn Senegal, sheep breeds have adapted to their environment and play a key socio-economic role. This study aimed to explore the genetic diversity and structure of four Senegalese sheep breeds (Peul-peul, Djallonke, Touabire, and Ladoum) and their relationships with global sheep breeds. To that end, forty-seven sheep were genotyped using the OvineSNP50 BeadChip, and these genotypic data were analysed with those of 73 sheep breeds representative of worldwide ovine diversity (2729 animals). The average observed heterozygosity (Ho) ranged from 0.293 in Djallonke sheep to 0.339 in Touabire sheep. The estimated Fis values were low, ranging from 0.019 for Ladoum to 0.034 for Peul-peul sheep. The estimated Fst values were low (0.003–0.044) among the trypanosusceptible breeds (Peul-peul, Touabire, and Ladoum) but high between the previous breeds and the trypanotolerant Djallonke breed (0.075–0.116), indicating better genetic conservation of the Djallonke sheep. A principal component analysis revealed clustering of the Senegalese sheep breeds according to their geographic distribution. However, owing to genetic improvement practices, the introgression of Touabire sheep blood seems to have reshaped the genetic landscape of the trypanosusceptible sheep breeds in Senegal. The Senegalese sheep breeds showed lower genetic diversity than their presumed ancestral sheep breeds of the Middle East. They also presented some relatedness with Caribbean sheep breeds, which reveals their contribution to the global genetic diversity and to the development of Caribbean sheep breeds.https://www.mdpi.com/2076-2615/12/12/1512SNPsheepSenegal |
| spellingShingle | Ayao Missohou Basse Kaboré Laurence Flori Simplice Bosco Ayssiwede Jean-Luc Hornick Marianne Raes Jean-François Cabaraux Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide Polymorphisms Animals SNP sheep Senegal |
| title | Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide Polymorphisms |
| title_full | Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide Polymorphisms |
| title_fullStr | Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide Polymorphisms |
| title_full_unstemmed | Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide Polymorphisms |
| title_short | Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide Polymorphisms |
| title_sort | analysis of the genetic diversity and population structure of four senegalese sheep breeds using medium density single nucleotide polymorphisms |
| topic | SNP sheep Senegal |
| url | https://www.mdpi.com/2076-2615/12/12/1512 |
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