Integrative bioinformatics analysis characterizing the role of EDC3 in mRNA decay and its association to intellectual disability

Abstract Background Decapping of mRNA is an important step in the regulation of mRNA turnover and therefore of gene expression, which is a key process controlling development and homeostasis of all organisms. It has been shown that EDC3 plays a role in mRNA decapping, however its function is not wel...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ute Scheller, Kathrin Pfisterer, Steffen Uebe, Arif B. Ekici, André Reis, Rami Jamra, Fulvia Ferrazzi
التنسيق: مقال
اللغة:English
منشور في: BMC 2018-04-01
سلاسل:BMC Medical Genomics
الموضوعات:
الوصول للمادة أونلاين:http://link.springer.com/article/10.1186/s12920-018-0358-6