Patterns of Coevolutionary Adaptations across Time and Space in Mouse Gammaretroviruses and Three Restrictive Host Factors

Patterns of Coevolutionary Adaptations across Time and Space in Mouse Gammaretroviruses and Three Restrictive Host Factors

The classical laboratory mouse strains are genetic mosaics of three <i>Mus musculus</i> subspecies that occupy distinct regions of Eurasia. These strains and subspecies carry infectious and endogenous mouse leukemia viruses (MLVs) that can be pathogenic and mutagenic. MLVs evolved in con...

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Bibliographic Details
Main Authors: Guney Boso, Oscar Lam, Devinka Bamunusinghe, Andrew J. Oler, Kurt Wollenberg, Qingping Liu, Esther Shaffer, Christine A. Kozak
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
mouse gammaretroviruses
restriction factors
endogenous retroviruses
positive selection
coevolution
<i>Fv1</i> restriction
Online Access:https://www.mdpi.com/1999-4915/13/9/1864

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