Synthesis and Biological Evaluation of Potential Oncoimmunomodulator Agents

Synthesis and Biological Evaluation of Potential Oncoimmunomodulator Agents

Fourteen triazole-scaffold derivatives were synthetized and biologically evaluated as potential oncoimmunomodultator agents by targeting both PD-L1 and c-Myc. First, the antiproliferative activity of these molecules on the monocultures of several tumor cell lines (HT-29, A-549, and MCF-7) and on the...

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Bibliographic Details
Main Authors:	Raquel Gil-Edo, Sara Espejo, Eva Falomir, Miguel Carda
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	International Journal of Molecular Sciences
Subjects:	PD-L1 c-Myc IL-6 multitarget inhibitors immunomodulation angiogenesis
Online Access:	https://www.mdpi.com/1422-0067/24/3/2614

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