Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPD
Background: Fine particulate matter (PM2.5) is a well-known risk factor for worse outcomes of chronic obstructive pulmonary disease (COPD). However, evidence-based guidance on effective personal behavioural strategies to minimise the effects of PM2.5 is limited. This study aimed to assess the effect...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | Environment International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412023005597 |
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| author | Jieun Kang Hwan-Cheol Kim Youngwon Jang Jung Bok Lee Jae Seung Lee Yeon-Mok Oh Hyun Woo Ji Ji Ye Jung Sei Won Lee |
| author_facet | Jieun Kang Hwan-Cheol Kim Youngwon Jang Jung Bok Lee Jae Seung Lee Yeon-Mok Oh Hyun Woo Ji Ji Ye Jung Sei Won Lee |
| author_sort | Jieun Kang |
| collection | DOAJ |
| description | Background: Fine particulate matter (PM2.5) is a well-known risk factor for worse outcomes of chronic obstructive pulmonary disease (COPD). However, evidence-based guidance on effective personal behavioural strategies to minimise the effects of PM2.5 is limited. This study aimed to assess the effectiveness of a behavioural intervention in reducing PM2.5 exposure and improving clinical outcomes in patients with COPD. Materials and Methods: Participants were 1:1 randomised, and the intervention group received a behavioural intervention consisting of five activities, while the control group received usual care. The participants were followed up for 9 months. The primary outcomes were differences in the score of St. George’s Respiratory Questionnaire for patients with COPD (SGRQ-C) and COPD assessment test (CAT) from baseline. Results: A total of 106 participants were enrolled and 102 completed the study. At the end of the study, the intervention group showed significant improvements in the primary outcomes compared to the control group, with a group difference of −5.9 in the reduction of total SGRQ-C (−3.4 vs. 2.5; p = 0.049) and −3.8 in the CAT score (−1.2 vs. 2.7; p = 0.001). Participants with good adherence to the intervention demonstrated a greater extent of improvement in CAT score and lower PM2.5 levels compared to those who had poor adherence or were in the control group. Regular checking of air quality forecasts was significantly associated with a reduction in CAT scores among all the intervention activities. Conclusion: Individual-level behavioural interventions can be an effective strategy for mitigating the health hazards associated with PM2.5.ClinicalTrials.gov Identifier: NCT04878367. |
| first_indexed | 2024-03-11T07:35:26Z |
| format | Article |
| id | doaj.art-f4ff9d4d99834536b220e10bb57c6749 |
| institution | Directory Open Access Journal |
| issn | 0160-4120 |
| language | English |
| last_indexed | 2024-03-11T07:35:26Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj.art-f4ff9d4d99834536b220e10bb57c67492023-11-17T05:24:52ZengElsevierEnvironment International0160-41202023-11-01181108286Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPDJieun Kang0Hwan-Cheol Kim1Youngwon Jang2Jung Bok Lee3Jae Seung Lee4Yeon-Mok Oh5Hyun Woo Ji6Ji Ye Jung7Sei Won Lee8Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of KoreaDepartment of Occupational and Environmental Medicine, Inha University College of Medicine, Incheon, Republic of KoreaDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of KoreaDepartment of Clinical Epidemiology and Biostatistics, Asan Medical Center, Seoul, Republic of KoreaDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of KoreaDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of KoreaDivision of Pulmonology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Republic of KoreaDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea; Corresponding authors.Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; Corresponding authors.Background: Fine particulate matter (PM2.5) is a well-known risk factor for worse outcomes of chronic obstructive pulmonary disease (COPD). However, evidence-based guidance on effective personal behavioural strategies to minimise the effects of PM2.5 is limited. This study aimed to assess the effectiveness of a behavioural intervention in reducing PM2.5 exposure and improving clinical outcomes in patients with COPD. Materials and Methods: Participants were 1:1 randomised, and the intervention group received a behavioural intervention consisting of five activities, while the control group received usual care. The participants were followed up for 9 months. The primary outcomes were differences in the score of St. George’s Respiratory Questionnaire for patients with COPD (SGRQ-C) and COPD assessment test (CAT) from baseline. Results: A total of 106 participants were enrolled and 102 completed the study. At the end of the study, the intervention group showed significant improvements in the primary outcomes compared to the control group, with a group difference of −5.9 in the reduction of total SGRQ-C (−3.4 vs. 2.5; p = 0.049) and −3.8 in the CAT score (−1.2 vs. 2.7; p = 0.001). Participants with good adherence to the intervention demonstrated a greater extent of improvement in CAT score and lower PM2.5 levels compared to those who had poor adherence or were in the control group. Regular checking of air quality forecasts was significantly associated with a reduction in CAT scores among all the intervention activities. Conclusion: Individual-level behavioural interventions can be an effective strategy for mitigating the health hazards associated with PM2.5.ClinicalTrials.gov Identifier: NCT04878367.http://www.sciencedirect.com/science/article/pii/S0160412023005597Chronic obstructive pulmonary diseaseAir pollutionParticulate matterBehavioural interventionQuality of life |
| spellingShingle | Jieun Kang Hwan-Cheol Kim Youngwon Jang Jung Bok Lee Jae Seung Lee Yeon-Mok Oh Hyun Woo Ji Ji Ye Jung Sei Won Lee Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPD Environment International Chronic obstructive pulmonary disease Air pollution Particulate matter Behavioural intervention Quality of life |
| title | Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPD |
| title_full | Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPD |
| title_fullStr | Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPD |
| title_full_unstemmed | Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPD |
| title_short | Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPD |
| title_sort | randomised controlled trial of a behavioural intervention to reduce exposure to pm2 5 in patients with copd |
| topic | Chronic obstructive pulmonary disease Air pollution Particulate matter Behavioural intervention Quality of life |
| url | http://www.sciencedirect.com/science/article/pii/S0160412023005597 |
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