Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review
Stevia rebaudiana Bertoni is a small perennial shrub of the Asteraceae (Compositae) family that is native to South America, particularly Brazil and Paraguay, where it is known as “stevia” or “honey leaf” for its powerful sweetness. Several studies have suggested that in addition to their sweetness,...
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MDPI AG
2015-12-01
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author | Gianmaria Fabrizio Ferrazzano Tiziana Cantile Brunella Alcidi Marco Coda Aniello Ingenito Armando Zarrelli Giovanni Di Fabio Antonino Pollio |
author_facet | Gianmaria Fabrizio Ferrazzano Tiziana Cantile Brunella Alcidi Marco Coda Aniello Ingenito Armando Zarrelli Giovanni Di Fabio Antonino Pollio |
author_sort | Gianmaria Fabrizio Ferrazzano |
collection | DOAJ |
description | Stevia rebaudiana Bertoni is a small perennial shrub of the Asteraceae (Compositae) family that is native to South America, particularly Brazil and Paraguay, where it is known as “stevia” or “honey leaf” for its powerful sweetness. Several studies have suggested that in addition to their sweetness, steviosides and their related compounds, including rebaudioside A and isosteviol, may offer additional therapeutic benefits. These benefits include anti-hyperglycaemic, anti-hypertensive, anti-inflammatory, anti-tumor, anti-diarrheal, diuretic, and immunomodulatory actions. Additionally, critical analysis of the literature supports the anti-bacterial role of steviosides on oral bacteria flora. The aim of this review is to show the emerging results regarding the anti-cariogenic properties of S. rebaudiana Bertoni. Data shown in the present paper provide evidence that stevioside extracts from S. rebaudiana are not cariogenic. Future research should be focused on in vivo studies to evaluate the effects on dental caries of regular consumption of S. rebaudiana extract-based products. |
first_indexed | 2024-04-12T09:42:46Z |
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id | doaj.art-f500d12dea784cfdac7b0d9d24e0dc35 |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-04-12T09:42:46Z |
publishDate | 2015-12-01 |
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series | Molecules |
spelling | doaj.art-f500d12dea784cfdac7b0d9d24e0dc352022-12-22T03:38:02ZengMDPI AGMolecules1420-30492015-12-012113810.3390/molecules21010038molecules21010038Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A ReviewGianmaria Fabrizio Ferrazzano0Tiziana Cantile1Brunella Alcidi2Marco Coda3Aniello Ingenito4Armando Zarrelli5Giovanni Di Fabio6Antonino Pollio7Department of Neuroscience, Reproductive and Oral Sciences, Section of Paediatric Dentistry, University of Naples, Federico II, Naples 80131, ItalyDepartment of Neuroscience, Reproductive and Oral Sciences, Section of Paediatric Dentistry, University of Naples, Federico II, Naples 80131, ItalyDepartment of Neuroscience, Reproductive and Oral Sciences, Section of Paediatric Dentistry, University of Naples, Federico II, Naples 80131, ItalyDepartment of Neuroscience, Reproductive and Oral Sciences, Section of Paediatric Dentistry, University of Naples, Federico II, Naples 80131, ItalyDepartment of Neuroscience, Reproductive and Oral Sciences, Section of Paediatric Dentistry, University of Naples, Federico II, Naples 80131, ItalyDepartment of Chemical Sciences, Complesso Universitario di Monte Sant’Angelo, Cupa Nuova Cintia, 21-80126-Napoli, University of Naples, Federico II, Naples 80126, ItalyDepartment of Chemical Sciences, Complesso Universitario di Monte Sant’Angelo, Cupa Nuova Cintia, 21-80126-Napoli, University of Naples, Federico II, Naples 80126, ItalyDepartment of Biology, Complesso Universitario di Monte Sant’Angelo, Cupa Nuova Cintia, 21-80126-Napoli, University of Naples, Federico II, Naples 80126, ItalyStevia rebaudiana Bertoni is a small perennial shrub of the Asteraceae (Compositae) family that is native to South America, particularly Brazil and Paraguay, where it is known as “stevia” or “honey leaf” for its powerful sweetness. Several studies have suggested that in addition to their sweetness, steviosides and their related compounds, including rebaudioside A and isosteviol, may offer additional therapeutic benefits. These benefits include anti-hyperglycaemic, anti-hypertensive, anti-inflammatory, anti-tumor, anti-diarrheal, diuretic, and immunomodulatory actions. Additionally, critical analysis of the literature supports the anti-bacterial role of steviosides on oral bacteria flora. The aim of this review is to show the emerging results regarding the anti-cariogenic properties of S. rebaudiana Bertoni. Data shown in the present paper provide evidence that stevioside extracts from S. rebaudiana are not cariogenic. Future research should be focused on in vivo studies to evaluate the effects on dental caries of regular consumption of S. rebaudiana extract-based products.http://www.mdpi.com/1420-3049/21/1/38Stevia rebaudiana Bertonidental cariessweetener |
spellingShingle | Gianmaria Fabrizio Ferrazzano Tiziana Cantile Brunella Alcidi Marco Coda Aniello Ingenito Armando Zarrelli Giovanni Di Fabio Antonino Pollio Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review Molecules Stevia rebaudiana Bertoni dental caries sweetener |
title | Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review |
title_full | Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review |
title_fullStr | Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review |
title_full_unstemmed | Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review |
title_short | Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review |
title_sort | is stevia rebaudiana bertoni a non cariogenic sweetener a review |
topic | Stevia rebaudiana Bertoni dental caries sweetener |
url | http://www.mdpi.com/1420-3049/21/1/38 |
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