Designing combination therapies with modeling chaperoned machine learning.

Chemotherapy resistance is a major challenge to the effective treatment of cancer. Thus, a systematic pipeline for the efficient identification of effective combination treatments could bring huge biomedical benefit. In order to facilitate rational design of combination therapies, we developed a com...

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Bibliographic Details
Main Authors: Yin Zhang, Julie M Huynh, Guan-Sheng Liu, Richard Ballweg, Kayenat S Aryeh, Andrew L Paek, Tongli Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007158

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