Validity of self-reported smoking cessation with carbon monoxide cut-off point – A systematic review and meta-analysis of diagnostic test accuracy studies
Background and Objective: Breathalyzer is a small, portable, easy-to-use device that is used to determine the abstinence status of a smoker exhaling carbon monoxide, as well as to validate the self-reported smoking abstinence of an individual. Our study objective is to determine the different carbon...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Indian Academy of Oral Medicine and Radiology |
| Subjects: | |
| Online Access: | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=4;spage=605;epage=609;aulast=Mukadam |
| _version_ | 1797232633897287680 |
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| author | Ajinkya Mukadam Sahana Hegde-Shetiya Sonal Kale |
| author_facet | Ajinkya Mukadam Sahana Hegde-Shetiya Sonal Kale |
| author_sort | Ajinkya Mukadam |
| collection | DOAJ |
| description | Background and Objective: Breathalyzer is a small, portable, easy-to-use device that is used to determine the abstinence status of a smoker exhaling carbon monoxide, as well as to validate the self-reported smoking abstinence of an individual. Our study objective is to determine the different carbon monoxide cut-off points of a Breathalyzer that can be used to validate self-reported smoking cessation. Materials and Methods: Observational and interventional studies using Breathalyzer as a diagnostic test published between January 1980 and August 2020 were eligible. QUADAS-2 was used to assess the quality of the included studies. Pooled sensitivity and specificity were calculated using random-effects model. Sub-group analysis was carried out by using differing cut-off values and brands. Results: A total of 22 (18,337 participants) manuscripts were included for review, out of which 10 (10,385 participants) were considered in the meta-analysis. A cut-off of 7–10 ppm using piCO+ Smokerlyzer device and any of the Bedfont devices gave a pooled sensitivity through sensitivity analysis of 93.5 (95% confidence interval [CI]: 88–97) and specificity ranged from of 89.3 (95% CI: 77.7–95.2) to 93.6 (87.1–96.9) for any of the devices. When meta-analysis was performed by combining all devices and cut-off ranges from 2 to 10 ppm through sensitivity analysis, at 6–7 ppm, the sensitivity obtained was 95 (84.2–98.5) and specificity was 88.5 (71.7–95.9). Conclusion: Self-reported abstinence was validated by piCO+ Smokerlyzer by Bedfont Scientific at 6–7 ppm when all devices and various cut-off points were combined for analysis. |
| first_indexed | 2024-04-24T16:03:23Z |
| format | Article |
| id | doaj.art-f502f39b9e5a4f6a83524076293d640e |
| institution | Directory Open Access Journal |
| issn | 0972-1363 |
| language | English |
| last_indexed | 2024-04-24T16:03:23Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Academy of Oral Medicine and Radiology |
| spelling | doaj.art-f502f39b9e5a4f6a83524076293d640e2024-04-01T06:03:03ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13632023-01-0135460560910.4103/jiaomr.jiaomr_133_22Validity of self-reported smoking cessation with carbon monoxide cut-off point – A systematic review and meta-analysis of diagnostic test accuracy studiesAjinkya MukadamSahana Hegde-ShetiyaSonal KaleBackground and Objective: Breathalyzer is a small, portable, easy-to-use device that is used to determine the abstinence status of a smoker exhaling carbon monoxide, as well as to validate the self-reported smoking abstinence of an individual. Our study objective is to determine the different carbon monoxide cut-off points of a Breathalyzer that can be used to validate self-reported smoking cessation. Materials and Methods: Observational and interventional studies using Breathalyzer as a diagnostic test published between January 1980 and August 2020 were eligible. QUADAS-2 was used to assess the quality of the included studies. Pooled sensitivity and specificity were calculated using random-effects model. Sub-group analysis was carried out by using differing cut-off values and brands. Results: A total of 22 (18,337 participants) manuscripts were included for review, out of which 10 (10,385 participants) were considered in the meta-analysis. A cut-off of 7–10 ppm using piCO+ Smokerlyzer device and any of the Bedfont devices gave a pooled sensitivity through sensitivity analysis of 93.5 (95% confidence interval [CI]: 88–97) and specificity ranged from of 89.3 (95% CI: 77.7–95.2) to 93.6 (87.1–96.9) for any of the devices. When meta-analysis was performed by combining all devices and cut-off ranges from 2 to 10 ppm through sensitivity analysis, at 6–7 ppm, the sensitivity obtained was 95 (84.2–98.5) and specificity was 88.5 (71.7–95.9). Conclusion: Self-reported abstinence was validated by piCO+ Smokerlyzer by Bedfont Scientific at 6–7 ppm when all devices and various cut-off points were combined for analysis.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=4;spage=605;epage=609;aulast=Mukadambreathalyzer testcarbon monoxidemeta-analysissmoking cessationvalidation study |
| spellingShingle | Ajinkya Mukadam Sahana Hegde-Shetiya Sonal Kale Validity of self-reported smoking cessation with carbon monoxide cut-off point – A systematic review and meta-analysis of diagnostic test accuracy studies Journal of Indian Academy of Oral Medicine and Radiology breathalyzer test carbon monoxide meta-analysis smoking cessation validation study |
| title | Validity of self-reported smoking cessation with carbon monoxide cut-off point – A systematic review and meta-analysis of diagnostic test accuracy studies |
| title_full | Validity of self-reported smoking cessation with carbon monoxide cut-off point – A systematic review and meta-analysis of diagnostic test accuracy studies |
| title_fullStr | Validity of self-reported smoking cessation with carbon monoxide cut-off point – A systematic review and meta-analysis of diagnostic test accuracy studies |
| title_full_unstemmed | Validity of self-reported smoking cessation with carbon monoxide cut-off point – A systematic review and meta-analysis of diagnostic test accuracy studies |
| title_short | Validity of self-reported smoking cessation with carbon monoxide cut-off point – A systematic review and meta-analysis of diagnostic test accuracy studies |
| title_sort | validity of self reported smoking cessation with carbon monoxide cut off point a systematic review and meta analysis of diagnostic test accuracy studies |
| topic | breathalyzer test carbon monoxide meta-analysis smoking cessation validation study |
| url | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=4;spage=605;epage=609;aulast=Mukadam |
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