PEGylated Strontium Sulfite Nanoparticles with Spontaneously Formed Surface-Embedded Protein Corona Restrict Off-Target Distribution and Accelerate Breast Tumour-Selective Delivery of siRNA
As transporters of RNAi therapeutics in preclinical and clinical studies, the application of nanoparticles is often hindered by their susceptibility to opsonin-mediated clearance, poor biological stability, ineffectual targeting, and undesirable effects on healthy cells. Prolonging the blood circula...
Main Authors: | Md. Emranul Karim, Ezharul Hoque Chowdhury |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Journal of Functional Biomaterials |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-4983/13/4/211 |
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