Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs
Abstract Background Alopecia areata (AA) is an autoimmune disease characterized by non-scarring hair loss in adults and children. Clinical manifestations range from hair loss in small, well-circumscribed patches to total hair loss on the scalp or any other hair-bearing areas. Although the exact path...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Adis, Springer Healthcare
2023-06-01
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| Series: | Dermatology and Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s13555-023-00946-8 |
| _version_ | 1797789949030825984 |
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| author | Anwar Al Hammadi Nisha V. Parmar Khadija Aljefri Osama Al Sharif Marwa Abdallah Haytham Mohamed Ahmed Alfred Ammoury |
| author_facet | Anwar Al Hammadi Nisha V. Parmar Khadija Aljefri Osama Al Sharif Marwa Abdallah Haytham Mohamed Ahmed Alfred Ammoury |
| author_sort | Anwar Al Hammadi |
| collection | DOAJ |
| description | Abstract Background Alopecia areata (AA) is an autoimmune disease characterized by non-scarring hair loss in adults and children. Clinical manifestations range from hair loss in small, well-circumscribed patches to total hair loss on the scalp or any other hair-bearing areas. Although the exact pathogenesis of AA is not fully understood, it is thought that loss of immune privilege caused by immunological dysregulation of the hair follicle is key. Genetic susceptibility also plays a role. Response to currently available treatments is widely variable, causing patient dissatisfaction and creating an unmet need. AA is frequently associated with multiple comorbidities, further affecting patient quality of life. Aims and Findings AA causes a significant burden on dermatologists and healthcare systems in the Middle East and Africa. There is a lack of data registries, local consensus, and treatment guidelines in the region. Limited public awareness, availability of treatments, and patient support need to be addressed to improve disease management in the region. A literature review was conducted to identify relevant publications and highlight regional data on prevalence rates, diagnosis, quality of life, treatment modalities, and unmet needs for AA in the Middle East and Africa. |
| first_indexed | 2024-03-13T01:57:55Z |
| format | Article |
| id | doaj.art-f5062935a42f494a9bbde90476bcd25a |
| institution | Directory Open Access Journal |
| issn | 2193-8210 2190-9172 |
| language | English |
| last_indexed | 2024-03-13T01:57:55Z |
| publishDate | 2023-06-01 |
| publisher | Adis, Springer Healthcare |
| record_format | Article |
| series | Dermatology and Therapy |
| spelling | doaj.art-f5062935a42f494a9bbde90476bcd25a2023-07-02T11:08:22ZengAdis, Springer HealthcareDermatology and Therapy2193-82102190-91722023-06-011371435146410.1007/s13555-023-00946-8Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet NeedsAnwar Al Hammadi0Nisha V. Parmar1Khadija Aljefri2Osama Al Sharif3Marwa Abdallah4Haytham Mohamed Ahmed5Alfred Ammoury6Department of Dermatology, Dermamed ClinicDepartment of Dermatology, Rashid Hospital, Dubai Health AuthorityDepartment of Dermatology, Dermamed ClinicKing Fahad General HospitalAin Shams UniversityPfizer Inc. LtdDivision of Dermatology, St George University Medical CenterAbstract Background Alopecia areata (AA) is an autoimmune disease characterized by non-scarring hair loss in adults and children. Clinical manifestations range from hair loss in small, well-circumscribed patches to total hair loss on the scalp or any other hair-bearing areas. Although the exact pathogenesis of AA is not fully understood, it is thought that loss of immune privilege caused by immunological dysregulation of the hair follicle is key. Genetic susceptibility also plays a role. Response to currently available treatments is widely variable, causing patient dissatisfaction and creating an unmet need. AA is frequently associated with multiple comorbidities, further affecting patient quality of life. Aims and Findings AA causes a significant burden on dermatologists and healthcare systems in the Middle East and Africa. There is a lack of data registries, local consensus, and treatment guidelines in the region. Limited public awareness, availability of treatments, and patient support need to be addressed to improve disease management in the region. A literature review was conducted to identify relevant publications and highlight regional data on prevalence rates, diagnosis, quality of life, treatment modalities, and unmet needs for AA in the Middle East and Africa.https://doi.org/10.1007/s13555-023-00946-8Alopecia areataDiagnosisDisease managementHair lossMPBMiddle East |
| spellingShingle | Anwar Al Hammadi Nisha V. Parmar Khadija Aljefri Osama Al Sharif Marwa Abdallah Haytham Mohamed Ahmed Alfred Ammoury Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs Dermatology and Therapy Alopecia areata Diagnosis Disease management Hair loss MPB Middle East |
| title | Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs |
| title_full | Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs |
| title_fullStr | Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs |
| title_full_unstemmed | Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs |
| title_short | Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs |
| title_sort | review on alopecia areata in the middle east and africa landscape and unmet needs |
| topic | Alopecia areata Diagnosis Disease management Hair loss MPB Middle East |
| url | https://doi.org/10.1007/s13555-023-00946-8 |
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