An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae

Small regulatory RNAs (sRNAs) often act in concert with the RNA-chaperone Hfq to regulate the expression of multiple target transcripts in bacteria. Here, the authors identify Hfq-interacting sRNAs and their targets in the pathogen Vibrio cholerae, including an RNA sponge that binds and inactivates...

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Bibliographic Details
Main Authors: Michaela Huber, Anne Lippegaus, Sahar Melamed, Malte Siemers, Benjamin R. Wucher, Mona Hoyos, Carey Nadell, Gisela Storz, Kai Papenfort
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35261-x

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