An Internal Promoter Drives the Expression of a Truncated Form of <i>CCC1</i> Capable of Protecting Yeast from Iron Toxicity

An Internal Promoter Drives the Expression of a Truncated Form of <i>CCC1</i> Capable of Protecting Yeast from Iron Toxicity

In yeast, iron storage and detoxification depend on the Ccc1 transporter that mediates iron accumulation in vacuoles. While deletion of the <i>CCC1</i> gene renders cells unable to survive under iron overload conditions, the deletion of its previously identified regulators only partially...

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Bibliographic Details
Main Authors: Catarina Amaral, Cristina Teixeira Vicente, Soraia Marques Caetano, Ana Gaspar-Cordeiro, Yang Yang, Peter Cloetens, Célia V. Romão, Claudina Rodrigues-Pousada, Catarina Pimentel
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Microorganisms
Subjects:
yeast
iron
gene expression
alternative promoter
vacuole
transcription
Online Access:https://www.mdpi.com/2076-2607/9/6/1337

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