Dymephosphone dermatoprotective activity under reduced blood circulation

Dermatoprotective activity (DPA) comparative evaluation of dymephosphone, actovegin, trental and meksidol under reduced blood circulation has been carried out. It has been proved that in experimental mice dymephosphone judging by DPA exceeds actovegin in quality by 2,8 times and is similar to meksid...

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Main Authors: D. A. Nefedov, A. V. Zelenskaya, N. A. Sabirova, P. A. Galenko-Yaroshevsky
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2015-10-01
Series:Кубанский научный медицинский вестник
Subjects:
Online Access:https://ksma.elpub.ru/jour/article/view/398
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author D. A. Nefedov
A. V. Zelenskaya
N. A. Sabirova
P. A. Galenko-Yaroshevsky
author_facet D. A. Nefedov
A. V. Zelenskaya
N. A. Sabirova
P. A. Galenko-Yaroshevsky
author_sort D. A. Nefedov
collection DOAJ
description Dermatoprotective activity (DPA) comparative evaluation of dymephosphone, actovegin, trental and meksidol under reduced blood circulation has been carried out. It has been proved that in experimental mice dymephosphone judging by DPA exceeds actovegin in quality by 2,8 times and is similar to meksidol. At the same time it is 5,2 times is worse than trental; as for its width of therapeutic activion (WTA) it is better than meksidol, trental and actovegin by 5.6, 1.8 and 2.9 times respectively. In experimental rats dymephosphone judging by DPA exceeds actovegin in quality by 3,6 times and is worse than trental and meksidol by 4.7 and 1.3 times respectively; as for the WTA it is better than actovegin, trental and meksidol by 3.8, 2.0, 5.5 times respectively.
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spelling doaj.art-f508fd4aaf2a424b91ec30c3338a3a652024-02-25T10:57:17ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442015-10-0159910510.25207/1608-6228-2015-5-99-105398Dymephosphone dermatoprotective activity under reduced blood circulationD. A. Nefedov0A. V. Zelenskaya1N. A. Sabirova2P. A. Galenko-Yaroshevsky3Krasnodar branch «IRTC «Eye microsurgery «them akad. S. N. Fyodorov» of the Ministry of health of RussiaKuban state medical university of the Ministry of health of RussiaKuban state medical university of the Ministry of health of RussiaKuban state medical university of the Ministry of health of RussiaDermatoprotective activity (DPA) comparative evaluation of dymephosphone, actovegin, trental and meksidol under reduced blood circulation has been carried out. It has been proved that in experimental mice dymephosphone judging by DPA exceeds actovegin in quality by 2,8 times and is similar to meksidol. At the same time it is 5,2 times is worse than trental; as for its width of therapeutic activion (WTA) it is better than meksidol, trental and actovegin by 5.6, 1.8 and 2.9 times respectively. In experimental rats dymephosphone judging by DPA exceeds actovegin in quality by 3,6 times and is worse than trental and meksidol by 4.7 and 1.3 times respectively; as for the WTA it is better than actovegin, trental and meksidol by 3.8, 2.0, 5.5 times respectively.https://ksma.elpub.ru/jour/article/view/398кожный лоскут на питающей ножкедимефосфонактовегинтренталмексидолtissue graft on feeding stalkdymephosphoneactovegintrentalmeksidoldermatoprotective activity
spellingShingle D. A. Nefedov
A. V. Zelenskaya
N. A. Sabirova
P. A. Galenko-Yaroshevsky
Dymephosphone dermatoprotective activity under reduced blood circulation
Кубанский научный медицинский вестник
кожный лоскут на питающей ножке
димефосфон
актовегин
трентал
мексидол
tissue graft on feeding stalk
dymephosphone
actovegin
trental
meksidol
dermatoprotective activity
title Dymephosphone dermatoprotective activity under reduced blood circulation
title_full Dymephosphone dermatoprotective activity under reduced blood circulation
title_fullStr Dymephosphone dermatoprotective activity under reduced blood circulation
title_full_unstemmed Dymephosphone dermatoprotective activity under reduced blood circulation
title_short Dymephosphone dermatoprotective activity under reduced blood circulation
title_sort dymephosphone dermatoprotective activity under reduced blood circulation
topic кожный лоскут на питающей ножке
димефосфон
актовегин
трентал
мексидол
tissue graft on feeding stalk
dymephosphone
actovegin
trental
meksidol
dermatoprotective activity
url https://ksma.elpub.ru/jour/article/view/398
work_keys_str_mv AT danefedov dymephosphonedermatoprotectiveactivityunderreducedbloodcirculation
AT avzelenskaya dymephosphonedermatoprotectiveactivityunderreducedbloodcirculation
AT nasabirova dymephosphonedermatoprotectiveactivityunderreducedbloodcirculation
AT pagalenkoyaroshevsky dymephosphonedermatoprotectiveactivityunderreducedbloodcirculation