Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRT
PurposeThis study aimed to investigate the dosimetric effect and delivery reliability of jaw tracking (JT) with increasing planning target volume (PTV) for lung stereotactic body radiation therapy (SBRT) plans. A threshold of PTV was proposed as a selection criterion between JT and fixed-jaw (FJ) te...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-02-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.820632/full |
| _version_ | 1819284569772261376 |
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| author | Wuji Sun Yinghua Shi Yu Li Chao Ge Xu Yang Wenming Xia Kunzhi Chen Libo Wang Lihua Dong Lihua Dong Lihua Dong Huidong Wang Huidong Wang |
| author_facet | Wuji Sun Yinghua Shi Yu Li Chao Ge Xu Yang Wenming Xia Kunzhi Chen Libo Wang Lihua Dong Lihua Dong Lihua Dong Huidong Wang Huidong Wang |
| author_sort | Wuji Sun |
| collection | DOAJ |
| description | PurposeThis study aimed to investigate the dosimetric effect and delivery reliability of jaw tracking (JT) with increasing planning target volume (PTV) for lung stereotactic body radiation therapy (SBRT) plans. A threshold of PTV was proposed as a selection criterion between JT and fixed-jaw (FJ) techniques.MethodsA total of 28 patients with early-stage non-small-cell lung cancer were retrospectively included. The PTVs ranged from 4.88 cc to 68.74 cc, prescribed with 48 Gy in four fractions. Three-partial-arc volumetric modulated arc therapy (VMAT) plans with FJ and with JT were created for each patient with the same optimization objectives. These two sets of plans were compared using metrics, including conformity index (CI), V50%, R50%, D2cm, dose–volume parameters of organs at risk, and monitor units (MUs). The ratio of small subfields (<3 cm in either dimension), %SS, was acquired as a surrogate for the small-field uncertainty. Statistical analyses were performed to evaluate the correlation between the differences in these parameters and the PTV.ResultsThe V50%, R50%, D2cm, and V20Gy, D1,500cc, and D1,000cc of the lung showed a statistically significant improvement in JT plans as opposed to FJ plans, while the number of MU in JT plans was higher by an average of 1.9%. Between FJ and JT plans, the PTV was strongly correlated with the differences in V50%, moderately correlated with those in V20Gy of the lung, and weakly correlated with those in D2cm and D1,500cc of the lung. By using JT, %SS was found to be negatively correlated with the PTV, and the PTV should be at least approximately 12.5 cc for an expected %SS <50%, which was 15 cc for a %SS <20% and 20 cc for a %SS <5%.ConclusionsConsidering the dosimetric differences and small-field uncertainties, JT could be selected using a PTV threshold, such as 12.5, 15, or 20 cc, on the basis of the demand of delivery reliability for lung SBRT. |
| first_indexed | 2024-12-24T01:49:28Z |
| format | Article |
| id | doaj.art-f50d8a481c694d7385effcc1a76cfd01 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-24T01:49:28Z |
| publishDate | 2022-02-01 |
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| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-f50d8a481c694d7385effcc1a76cfd012022-12-21T17:21:47ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-02-011210.3389/fonc.2022.820632820632Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRTWuji Sun0Yinghua Shi1Yu Li2Chao Ge3Xu Yang4Wenming Xia5Kunzhi Chen6Libo Wang7Lihua Dong8Lihua Dong9Lihua Dong10Huidong Wang11Huidong Wang12Department of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaJilin Provincial Key Laboratory of Radiation Oncology and Therapy, Department of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaNational Health Commission (NHC) Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun, ChinaDepartment of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaJilin Provincial Key Laboratory of Radiation Oncology and Therapy, Department of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, ChinaPurposeThis study aimed to investigate the dosimetric effect and delivery reliability of jaw tracking (JT) with increasing planning target volume (PTV) for lung stereotactic body radiation therapy (SBRT) plans. A threshold of PTV was proposed as a selection criterion between JT and fixed-jaw (FJ) techniques.MethodsA total of 28 patients with early-stage non-small-cell lung cancer were retrospectively included. The PTVs ranged from 4.88 cc to 68.74 cc, prescribed with 48 Gy in four fractions. Three-partial-arc volumetric modulated arc therapy (VMAT) plans with FJ and with JT were created for each patient with the same optimization objectives. These two sets of plans were compared using metrics, including conformity index (CI), V50%, R50%, D2cm, dose–volume parameters of organs at risk, and monitor units (MUs). The ratio of small subfields (<3 cm in either dimension), %SS, was acquired as a surrogate for the small-field uncertainty. Statistical analyses were performed to evaluate the correlation between the differences in these parameters and the PTV.ResultsThe V50%, R50%, D2cm, and V20Gy, D1,500cc, and D1,000cc of the lung showed a statistically significant improvement in JT plans as opposed to FJ plans, while the number of MU in JT plans was higher by an average of 1.9%. Between FJ and JT plans, the PTV was strongly correlated with the differences in V50%, moderately correlated with those in V20Gy of the lung, and weakly correlated with those in D2cm and D1,500cc of the lung. By using JT, %SS was found to be negatively correlated with the PTV, and the PTV should be at least approximately 12.5 cc for an expected %SS <50%, which was 15 cc for a %SS <20% and 20 cc for a %SS <5%.ConclusionsConsidering the dosimetric differences and small-field uncertainties, JT could be selected using a PTV threshold, such as 12.5, 15, or 20 cc, on the basis of the demand of delivery reliability for lung SBRT.https://www.frontiersin.org/articles/10.3389/fonc.2022.820632/fullstereotactic body radiation therapyjaw tracking techniquevolumetric modulated arc therapyplanning target volumesmall field |
| spellingShingle | Wuji Sun Yinghua Shi Yu Li Chao Ge Xu Yang Wenming Xia Kunzhi Chen Libo Wang Lihua Dong Lihua Dong Lihua Dong Huidong Wang Huidong Wang Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRT Frontiers in Oncology stereotactic body radiation therapy jaw tracking technique volumetric modulated arc therapy planning target volume small field |
| title | Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRT |
| title_full | Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRT |
| title_fullStr | Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRT |
| title_full_unstemmed | Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRT |
| title_short | Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRT |
| title_sort | selection strategy of jaw tracking in vmat planning for lung sbrt |
| topic | stereotactic body radiation therapy jaw tracking technique volumetric modulated arc therapy planning target volume small field |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.820632/full |
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