Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT study
Objectives To evaluate the feasibility of radiofrequency ablation (RFA) on follicular neoplasm with low standard uptake value (SUV) in a Positron emission tomography (PET/CT) study. Methods From January 2018 to July 2019, 86 consecutive patients were diagnosed with follicular neoplasm. Of the patien...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
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Taylor & Francis Group
2021-01-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | http://dx.doi.org/10.1080/02656736.2021.1912414 |
| _version_ | 1818967668268466176 |
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| author | Wei-Che Lin Yu-Cheng Tung Yen-Hsiang Chang Sheng-Dean Luo Pi-Ling Chiang Shun Chen Huang Wei-Chih Chen Chen-Kai Chou Yan-Ye Su Wen-Chieh Chen Shun-Yu Chi Jung Hwan Baek |
| author_facet | Wei-Che Lin Yu-Cheng Tung Yen-Hsiang Chang Sheng-Dean Luo Pi-Ling Chiang Shun Chen Huang Wei-Chih Chen Chen-Kai Chou Yan-Ye Su Wen-Chieh Chen Shun-Yu Chi Jung Hwan Baek |
| author_sort | Wei-Che Lin |
| collection | DOAJ |
| description | Objectives To evaluate the feasibility of radiofrequency ablation (RFA) on follicular neoplasm with low standard uptake value (SUV) in a Positron emission tomography (PET/CT) study. Methods From January 2018 to July 2019, 86 consecutive patients were diagnosed with follicular neoplasm. Of the patients, 28 with PET/CT scans were enrolled in this study. All patients received ultrasound, fine/core needle aspiration, and PET/CT scan prior to treatment. In accordance with previous studies, we recommended 6 patients who had follicular neoplasm with SUVmax ≥5 undergo surgical resection due to an elevated suspicion of malignancy. For 22 patients SUVmax <5, RFA was performed using the moving shot technique. Ultrasound was performed 6 to 12 months after each procedure. Results Statistically significant volume reductions during follow-up between values prior to RFA and 12 months post RFA were demonstrated (12.6 ± 20.9 vs. 2.4 ± 3.0 cm3, p < 0.001). Volume reduction ratios at 6–12 months (mean: 10.1 months) after RFA were 73.3% ± 17.7%. One patient presented with vocal cord palsy and recovered within 3 months after RFA. No postprocedural hypothyroidism occurred in the RFA patients. Conclusions By using PET/CT, we can select patients with low SUV follicular neoplasm. RFA offers a safe and feasible alternative treatment option for patients unsuitable or unwilling to undergo surgery.KEY POINTS By using positron emission tomography-computed tomography, we can distinguish low SUV follicular neoplasm for radiofrequency ablation. For low SUV follicular neoplasm, RF ablation offers a safe and effective alternative treatment option for patients unsuitable or unwilling to undergo surgery. |
| first_indexed | 2024-12-20T13:52:27Z |
| format | Article |
| id | doaj.art-f50d8ed6cbef4552ac988115e3ae0fa6 |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-12-20T13:52:27Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-f50d8ed6cbef4552ac988115e3ae0fa62022-12-21T19:38:30ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572021-01-0138196396910.1080/02656736.2021.19124141912414Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT studyWei-Che Lin0Yu-Cheng Tung1Yen-Hsiang Chang2Sheng-Dean Luo3Pi-Ling Chiang4Shun Chen Huang5Wei-Chih Chen6Chen-Kai Chou7Yan-Ye Su8Wen-Chieh Chen9Shun-Yu Chi10Jung Hwan Baek11Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Pathology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical CenterObjectives To evaluate the feasibility of radiofrequency ablation (RFA) on follicular neoplasm with low standard uptake value (SUV) in a Positron emission tomography (PET/CT) study. Methods From January 2018 to July 2019, 86 consecutive patients were diagnosed with follicular neoplasm. Of the patients, 28 with PET/CT scans were enrolled in this study. All patients received ultrasound, fine/core needle aspiration, and PET/CT scan prior to treatment. In accordance with previous studies, we recommended 6 patients who had follicular neoplasm with SUVmax ≥5 undergo surgical resection due to an elevated suspicion of malignancy. For 22 patients SUVmax <5, RFA was performed using the moving shot technique. Ultrasound was performed 6 to 12 months after each procedure. Results Statistically significant volume reductions during follow-up between values prior to RFA and 12 months post RFA were demonstrated (12.6 ± 20.9 vs. 2.4 ± 3.0 cm3, p < 0.001). Volume reduction ratios at 6–12 months (mean: 10.1 months) after RFA were 73.3% ± 17.7%. One patient presented with vocal cord palsy and recovered within 3 months after RFA. No postprocedural hypothyroidism occurred in the RFA patients. Conclusions By using PET/CT, we can select patients with low SUV follicular neoplasm. RFA offers a safe and feasible alternative treatment option for patients unsuitable or unwilling to undergo surgery.KEY POINTS By using positron emission tomography-computed tomography, we can distinguish low SUV follicular neoplasm for radiofrequency ablation. For low SUV follicular neoplasm, RF ablation offers a safe and effective alternative treatment option for patients unsuitable or unwilling to undergo surgery.http://dx.doi.org/10.1080/02656736.2021.1912414thyroid glandfollicular neoplasmultrasoundf-18 fdg pet/ctablation technique |
| spellingShingle | Wei-Che Lin Yu-Cheng Tung Yen-Hsiang Chang Sheng-Dean Luo Pi-Ling Chiang Shun Chen Huang Wei-Chih Chen Chen-Kai Chou Yan-Ye Su Wen-Chieh Chen Shun-Yu Chi Jung Hwan Baek Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT study International Journal of Hyperthermia thyroid gland follicular neoplasm ultrasound f-18 fdg pet/ct ablation technique |
| title | Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT study |
| title_full | Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT study |
| title_fullStr | Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT study |
| title_full_unstemmed | Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT study |
| title_short | Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT study |
| title_sort | radiofrequency ablation for treatment of thyroid follicular neoplasm with low suv in pet ct study |
| topic | thyroid gland follicular neoplasm ultrasound f-18 fdg pet/ct ablation technique |
| url | http://dx.doi.org/10.1080/02656736.2021.1912414 |
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