A Human Organoid Model of Aggressive Hepatoblastoma for Disease Modeling and Drug Testing

Hepatoblastoma is the most common childhood liver cancer. Although survival has improved significantly over the past few decades, there remains a group of children with aggressive disease who do not respond to current treatment regimens. There is a critical need for novel models to study aggressive...

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Bibliographic Details
Main Authors: James A. Saltsman, William J. Hammond, Nicole J. C. Narayan, David Requena, Helmuth Gehart, Gadi Lalazar, Michael P. LaQuaglia, Hans Clevers, Sanford Simon
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/9/2668

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