Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus
Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) su...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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The Royal Society
2018-01-01
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| Series: | Royal Society Open Science |
| Subjects: | |
| Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.172466 |
| _version_ | 1818383829410250752 |
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| author | Shuihong Li Qianqian Mou Xinya Xu Shuhua Qi Polly H. M. Leung |
| author_facet | Shuihong Li Qianqian Mou Xinya Xu Shuhua Qi Polly H. M. Leung |
| author_sort | Shuihong Li |
| collection | DOAJ |
| description | Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections. |
| first_indexed | 2024-12-14T03:12:35Z |
| format | Article |
| id | doaj.art-f512cc4084184a0ba5f634564b95e63f |
| institution | Directory Open Access Journal |
| issn | 2054-5703 |
| language | English |
| last_indexed | 2024-12-14T03:12:35Z |
| publishDate | 2018-01-01 |
| publisher | The Royal Society |
| record_format | Article |
| series | Royal Society Open Science |
| spelling | doaj.art-f512cc4084184a0ba5f634564b95e63f2022-12-21T23:19:14ZengThe Royal SocietyRoyal Society Open Science2054-57032018-01-015510.1098/rsos.172466172466Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureusShuihong LiQianqian MouXinya XuShuhua QiPolly H. M. LeungPenicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.172466penicillenolssynergistic antibacterial activitymethicillin-resistant staphylococcus aureus |
| spellingShingle | Shuihong Li Qianqian Mou Xinya Xu Shuhua Qi Polly H. M. Leung Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus Royal Society Open Science penicillenols synergistic antibacterial activity methicillin-resistant staphylococcus aureus |
| title | Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus |
| title_full | Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus |
| title_fullStr | Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus |
| title_full_unstemmed | Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus |
| title_short | Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus |
| title_sort | synergistic antibacterial activity between penicillenols and antibiotics against methicillin resistant staphylococcus aureus |
| topic | penicillenols synergistic antibacterial activity methicillin-resistant staphylococcus aureus |
| url | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.172466 |
| work_keys_str_mv | AT shuihongli synergisticantibacterialactivitybetweenpenicillenolsandantibioticsagainstmethicillinresistantstaphylococcusaureus AT qianqianmou synergisticantibacterialactivitybetweenpenicillenolsandantibioticsagainstmethicillinresistantstaphylococcusaureus AT xinyaxu synergisticantibacterialactivitybetweenpenicillenolsandantibioticsagainstmethicillinresistantstaphylococcusaureus AT shuhuaqi synergisticantibacterialactivitybetweenpenicillenolsandantibioticsagainstmethicillinresistantstaphylococcusaureus AT pollyhmleung synergisticantibacterialactivitybetweenpenicillenolsandantibioticsagainstmethicillinresistantstaphylococcusaureus |