Brain endothelial LRP1 maintains blood–brain barrier integrity

Abstract The entry of blood-borne molecules into the brain is restricted by the blood–brain barrier (BBB). Various physical, transport and immune properties tightly regulate molecule movement between the blood and the brain to maintain brain homeostasis. A recent study utilizing a pan-endothelial, c...

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Bibliographic Details
Main Authors: Steffen E. Storck, Magdalena Kurtyka, Claus U. Pietrzik
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-021-00260-5