Multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma – A case report and review of the literature
Background: Primary cardiac undifferentiated pleomorphic sarcomas (UPS) are very rare entities with a myriad of potential presentations. Multiorgan embolism can result in significant morbidity and mortality in the absence of early recognition and timely intervention. This case report describes a pat...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Annals of Vascular Surgery - Brief Reports and Innovations |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772687822000721 |
| _version_ | 1797788428100698112 |
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| author | Joel Jia Yi Soon Schin Bek Kok Hooi Yap Shaun Qing-Wei Lee |
| author_facet | Joel Jia Yi Soon Schin Bek Kok Hooi Yap Shaun Qing-Wei Lee |
| author_sort | Joel Jia Yi Soon |
| collection | DOAJ |
| description | Background: Primary cardiac undifferentiated pleomorphic sarcomas (UPS) are very rare entities with a myriad of potential presentations. Multiorgan embolism can result in significant morbidity and mortality in the absence of early recognition and timely intervention. This case report describes a patient who received treatment for the abovementioned pathology and a literature review of available evidence on primary cardiac neoplasms was performed. Case presentation: This case is a 62-year-old female with cardioembolic stroke due to a left atrial mass. On hospital day 10 prior to operative intervention, the patient developed renovisceral and bilateral common iliac artery thromboemboli leading to acute limb ischemia and underwent bilateral femoral cutdown with aortoiliac thromboembolectomy. There was no mesenteric ischemia. Histopathological assessment of the emboli revealed primary cardiac undifferentiated pleomorphic sarcoma. She developed a catastrophic hemorrhagic stroke while on therapeutic anticoagulation which led to withdrawal of care. Conclusion: The literature review and case report demonstrate the need for timely intervention, judicial use of anticoagulation and histological assessment of emboli in cases of cardioembolic phenomena from an underlying cardiac neoplasm. |
| first_indexed | 2024-03-13T01:35:27Z |
| format | Article |
| id | doaj.art-f5181e51c49f4db78faaa00bcedb388b |
| institution | Directory Open Access Journal |
| issn | 2772-6878 |
| language | English |
| last_indexed | 2024-03-13T01:35:27Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Vascular Surgery - Brief Reports and Innovations |
| spelling | doaj.art-f5181e51c49f4db78faaa00bcedb388b2023-07-04T05:11:51ZengElsevierAnnals of Vascular Surgery - Brief Reports and Innovations2772-68782022-09-0123100110Multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma – A case report and review of the literatureJoel Jia Yi Soon0Schin Bek1Kok Hooi Yap2Shaun Qing-Wei Lee3Department of Vascular Surgery, Singapore General Hospital, Singapore; Corresponding author at: Department of General Surgery, Singapore Health Services, Outram Road 169608, Singapore.Yong Loo Lin School of Medicine, National University of Singapore, SingaporeDepartment of Cardiothoracic Surgery, National Heart Centre, Singapore General Hospital, SingaporeDepartment of Vascular Surgery, Singapore General Hospital, SingaporeBackground: Primary cardiac undifferentiated pleomorphic sarcomas (UPS) are very rare entities with a myriad of potential presentations. Multiorgan embolism can result in significant morbidity and mortality in the absence of early recognition and timely intervention. This case report describes a patient who received treatment for the abovementioned pathology and a literature review of available evidence on primary cardiac neoplasms was performed. Case presentation: This case is a 62-year-old female with cardioembolic stroke due to a left atrial mass. On hospital day 10 prior to operative intervention, the patient developed renovisceral and bilateral common iliac artery thromboemboli leading to acute limb ischemia and underwent bilateral femoral cutdown with aortoiliac thromboembolectomy. There was no mesenteric ischemia. Histopathological assessment of the emboli revealed primary cardiac undifferentiated pleomorphic sarcoma. She developed a catastrophic hemorrhagic stroke while on therapeutic anticoagulation which led to withdrawal of care. Conclusion: The literature review and case report demonstrate the need for timely intervention, judicial use of anticoagulation and histological assessment of emboli in cases of cardioembolic phenomena from an underlying cardiac neoplasm.http://www.sciencedirect.com/science/article/pii/S2772687822000721Cardiac sarcomaUndifferentiated pleomorphic sarcomaEmbolism |
| spellingShingle | Joel Jia Yi Soon Schin Bek Kok Hooi Yap Shaun Qing-Wei Lee Multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma – A case report and review of the literature Annals of Vascular Surgery - Brief Reports and Innovations Cardiac sarcoma Undifferentiated pleomorphic sarcoma Embolism |
| title | Multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma – A case report and review of the literature |
| title_full | Multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma – A case report and review of the literature |
| title_fullStr | Multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma – A case report and review of the literature |
| title_full_unstemmed | Multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma – A case report and review of the literature |
| title_short | Multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma – A case report and review of the literature |
| title_sort | multiorgan embolism from primary cardiac undifferentiated pleomorphic sarcoma a case report and review of the literature |
| topic | Cardiac sarcoma Undifferentiated pleomorphic sarcoma Embolism |
| url | http://www.sciencedirect.com/science/article/pii/S2772687822000721 |
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