Transplantation of iPSC-derived corneal endothelial substitutes in a monkey corneal edema model

Transplantation of iPSC-derived corneal endothelial substitutes in a monkey corneal edema model

Objective: In order to provide regenerative therapy for millions of patients suffering from corneal blindness globally, we derived corneal endothelial cell substitute (CECSi) cells from induced pluripotent stem cells (iPSCs) to treat corneal edema due to endothelial dysfunction (bullous keratopathy)...

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Bibliographic Details
Main Authors: Shin Hatou, Tomoko Sayano, Kazunari Higa, Emi Inagaki, Yuji Okano, Yasunori Sato, Hideyuki Okano, Kazuo Tsubota, Shigeto Shimmura
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Stem Cell Research
Subjects:
iPS cells
Cornea
Transplantation
Cell therapy
Bullous keratopathy
Translational medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121003445

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