Diagnosis and treatment of prediabetes as prevention of type 2 diabetes: A review
Prediabetes is defined as a disorder in which the criteria for diabetes mellitus are not met, but normal blood glucose values are exceeded; this intermediate hyperglycemia is associated with a high risk of developing diabetes and cardiovascular disease. The number of patients with diabetes mellitus...
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| Format: | Article |
| Language: | Russian |
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ZAO "Consilium Medicum"
2023-07-01
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| Series: | Consilium Medicum |
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| Online Access: | https://consilium.orscience.ru/2075-1753/article/viewFile/568228/133632 |
| _version_ | 1797741800046198784 |
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| author | Nina A. Petunina Narine S. Martirosian Mikhail V. Khachaturov Maria A. Zhutaeva Anastasiia A. Shaposhnikova Elizaveta V. Karpenko Zaynab A. Abdulganieva |
| author_facet | Nina A. Petunina Narine S. Martirosian Mikhail V. Khachaturov Maria A. Zhutaeva Anastasiia A. Shaposhnikova Elizaveta V. Karpenko Zaynab A. Abdulganieva |
| author_sort | Nina A. Petunina |
| collection | DOAJ |
| description | Prediabetes is defined as a disorder in which the criteria for diabetes mellitus are not met, but normal blood glucose values are exceeded; this intermediate hyperglycemia is associated with a high risk of developing diabetes and cardiovascular disease. The number of patients with diabetes mellitus continues to grow steadily, and therefore the role of timely interventions at the stage of prediabetes is obvious. A modern approach to preventing the progression of prediabetes includes correcting risk factors for cardiovascular diseases, arterial hypertension, dyslipidemia, weight loss and/or prevention of weight gain, and improving the quality of life. The first-line therapy for prediabetes is lifestyle modification, which includes changes in diet, physical activity, weight management, bad habits, and sleep hygiene. Thus, a non-pharmacological approach to the treatment of patients, aimed at reducing excess weight, plays a major role. In conditions of insufficient effectiveness of measures to change lifestyle, it is advisable to prescribe drug therapy. Metformin is the first-line drug for preventing the progression of carbohydrate metabolism disorders. In addition to lifestyle modification, orlistat, drugs from the group of GLP-1 analogues, thiazolidinediones, and acarbose have also demonstrated their effectiveness. Bariatric surgery is associated with improved glycemic control in prediabetic patients. |
| first_indexed | 2024-03-12T14:31:54Z |
| format | Article |
| id | doaj.art-f51ab0aa31924868aa2871238dc4d0ec |
| institution | Directory Open Access Journal |
| issn | 2075-1753 2542-2170 |
| language | Russian |
| last_indexed | 2024-03-12T14:31:54Z |
| publishDate | 2023-07-01 |
| publisher | ZAO "Consilium Medicum" |
| record_format | Article |
| series | Consilium Medicum |
| spelling | doaj.art-f51ab0aa31924868aa2871238dc4d0ec2023-08-17T12:55:55ZrusZAO "Consilium Medicum"Consilium Medicum2075-17532542-21702023-07-0125422923510.26442/20751753.2023.4.2023124708Diagnosis and treatment of prediabetes as prevention of type 2 diabetes: A reviewNina A. Petunina0https://orcid.org/0000-0001-9390-1200Narine S. Martirosian1https://orcid.org/0000-0002-0202-1257Mikhail V. Khachaturov2https://orcid.org/0000-0001-7606-6565Maria A. Zhutaeva3https://orcid.org/0009-0001-3706-3414Anastasiia A. Shaposhnikova4https://orcid.org/0009-0008-1579-1817Elizaveta V. Karpenko5https://orcid.org/0009-0009-4727-298XZaynab A. Abdulganieva6https://orcid.org/0009-0009-9393-4999Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Prediabetes is defined as a disorder in which the criteria for diabetes mellitus are not met, but normal blood glucose values are exceeded; this intermediate hyperglycemia is associated with a high risk of developing diabetes and cardiovascular disease. The number of patients with diabetes mellitus continues to grow steadily, and therefore the role of timely interventions at the stage of prediabetes is obvious. A modern approach to preventing the progression of prediabetes includes correcting risk factors for cardiovascular diseases, arterial hypertension, dyslipidemia, weight loss and/or prevention of weight gain, and improving the quality of life. The first-line therapy for prediabetes is lifestyle modification, which includes changes in diet, physical activity, weight management, bad habits, and sleep hygiene. Thus, a non-pharmacological approach to the treatment of patients, aimed at reducing excess weight, plays a major role. In conditions of insufficient effectiveness of measures to change lifestyle, it is advisable to prescribe drug therapy. Metformin is the first-line drug for preventing the progression of carbohydrate metabolism disorders. In addition to lifestyle modification, orlistat, drugs from the group of GLP-1 analogues, thiazolidinediones, and acarbose have also demonstrated their effectiveness. Bariatric surgery is associated with improved glycemic control in prediabetic patients.https://consilium.orscience.ru/2075-1753/article/viewFile/568228/133632prediabetestype 2 diabetesdiabetes preventionlifestyle modification |
| spellingShingle | Nina A. Petunina Narine S. Martirosian Mikhail V. Khachaturov Maria A. Zhutaeva Anastasiia A. Shaposhnikova Elizaveta V. Karpenko Zaynab A. Abdulganieva Diagnosis and treatment of prediabetes as prevention of type 2 diabetes: A review Consilium Medicum prediabetes type 2 diabetes diabetes prevention lifestyle modification |
| title | Diagnosis and treatment of prediabetes as prevention of type 2 diabetes: A review |
| title_full | Diagnosis and treatment of prediabetes as prevention of type 2 diabetes: A review |
| title_fullStr | Diagnosis and treatment of prediabetes as prevention of type 2 diabetes: A review |
| title_full_unstemmed | Diagnosis and treatment of prediabetes as prevention of type 2 diabetes: A review |
| title_short | Diagnosis and treatment of prediabetes as prevention of type 2 diabetes: A review |
| title_sort | diagnosis and treatment of prediabetes as prevention of type 2 diabetes a review |
| topic | prediabetes type 2 diabetes diabetes prevention lifestyle modification |
| url | https://consilium.orscience.ru/2075-1753/article/viewFile/568228/133632 |
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