Anti-cisplatin-induced Renal-injury Effect of Human Manganese Superoxide Dismutase with Leader Peptide

Anti-cisplatin-induced Renal-injury Effect of Human Manganese Superoxide Dismutase with Leader Peptide

Objective To investigate the effect of the fusion of leader peptide on the structure of human manganese superoxide dismutase (SOD2) and anti-cisplatin (DDP)-induced renal injury. Methods The effect of mitochondrion targeting sequence (MTS) on the structure and activity of SOD2 was analyzed by struct...

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Bibliographic Details
Main Authors: PAN Jianru, HAN Ya'nan, HE Xiaqi, YE Xiaoqiang, HE Huocong
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2023-07-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
manganese superoxide dismutase
leader peptide
cisplatin
renal injury
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.1465

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