Development of Taccalonolide AJ-Hydroxypropyl-β-Cyclodextrin Inclusion Complexes for Treatment of Clear Cell Renal-Cell Carcinoma
Background: Microtubule-targeted drugs are the most effective drugs for adult patients with certain solid tumors. Taccalonolide AJ (AJ) can stabilize tubulin polymerization by covalently binding to β-tubulin, which enables it to play a role in the treatment of tumors. However, its clinical applicati...
Main Authors: | Jing Han, Siwang Zhang, Junxin Niu, Chunli Zhang, Weichen Dai, Yuanyuan Wu, Lihong Hu |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/23/5586 |
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