Expression of Monocarboxylate Transporter 1 in Immunosuppressive Macrophages Is Associated With the Poor Prognosis in Breast Cancer

Expression of Monocarboxylate Transporter 1 in Immunosuppressive Macrophages Is Associated With the Poor Prognosis in Breast Cancer

Monocarboxylate transporter 1 (MCT1) participates in the transport of lactate to facilitate metabolic reprogramming during tumor progression. Tumor-associated macrophages (TAMs) are also involved in the inflammatory adaptation of the tumor microenvironment (TME). This study aimed to determine the co...

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Bibliographic Details
Main Authors: Bei Li, Qian Yang, Zhiyu Li, Zhiliang Xu, Si Sun, Qi Wu, Shengrong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
breast cancer
tumor-associated macrophage
MCT1
CD163
recurrence-free survival
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.574787/full

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