Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application

The baroreceptor reflex is an essential mechanism for the autonomic nervous system in cardiovascular homeostasis and is closely related to pain regulation. Baroreflex sensitivity (BRS) is an indicator for quantitative evaluation of baroreflex reflex function. Pain sensitivity is negatively correlate...

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Main Authors: CUI Quexuan, CHE Lu, XU Li
Format: Article
Language:zho
Published: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2024-03-01
Series:Xiehe Yixue Zazhi
Subjects:
Online Access:https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0552
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author CUI Quexuan
CHE Lu
XU Li
author_facet CUI Quexuan
CHE Lu
XU Li
author_sort CUI Quexuan
collection DOAJ
description The baroreceptor reflex is an essential mechanism for the autonomic nervous system in cardiovascular homeostasis and is closely related to pain regulation. Baroreflex sensitivity (BRS) is an indicator for quantitative evaluation of baroreflex reflex function. Pain sensitivity is negatively correlated with BRS, therefore, BRS has potential application prospects in pain risk prediction and therapeutic efficacy assessment. Vagus nerve stimulation, capable of activating the baroreceptor reflex, has been widely used in acute or chronic pain patients in recent years. This article reviews the mechanism and clinical application progress of the baroreceptor reflex in pain regulation, with the hope of providing reference for further exploring treatment to regulate baroreceptor reflex function in pain treatment.
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spelling doaj.art-f5215bf1c54148648623942965f449c82024-04-07T00:28:46ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812024-03-0115225826410.12290/xhyxzz.2023-0552Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical ApplicationCUI QuexuanCHE LuXU LiThe baroreceptor reflex is an essential mechanism for the autonomic nervous system in cardiovascular homeostasis and is closely related to pain regulation. Baroreflex sensitivity (BRS) is an indicator for quantitative evaluation of baroreflex reflex function. Pain sensitivity is negatively correlated with BRS, therefore, BRS has potential application prospects in pain risk prediction and therapeutic efficacy assessment. Vagus nerve stimulation, capable of activating the baroreceptor reflex, has been widely used in acute or chronic pain patients in recent years. This article reviews the mechanism and clinical application progress of the baroreceptor reflex in pain regulation, with the hope of providing reference for further exploring treatment to regulate baroreceptor reflex function in pain treatment.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0552baroreceptor reflexautonomic nervepainvagus nerve stimulationbaroreflex sensitivity
spellingShingle CUI Quexuan
CHE Lu
XU Li
Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application
Xiehe Yixue Zazhi
baroreceptor reflex
autonomic nerve
pain
vagus nerve stimulation
baroreflex sensitivity
title Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application
title_full Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application
title_fullStr Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application
title_full_unstemmed Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application
title_short Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application
title_sort baroreflex in pain regulation pathogenic mechanism and clinical application
topic baroreceptor reflex
autonomic nerve
pain
vagus nerve stimulation
baroreflex sensitivity
url https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0552
work_keys_str_mv AT cuiquexuan baroreflexinpainregulationpathogenicmechanismandclinicalapplication
AT chelu baroreflexinpainregulationpathogenicmechanismandclinicalapplication
AT xuli baroreflexinpainregulationpathogenicmechanismandclinicalapplication