Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application
The baroreceptor reflex is an essential mechanism for the autonomic nervous system in cardiovascular homeostasis and is closely related to pain regulation. Baroreflex sensitivity (BRS) is an indicator for quantitative evaluation of baroreflex reflex function. Pain sensitivity is negatively correlate...
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Format: | Article |
Language: | zho |
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Editorial Office of Medical Journal of Peking Union Medical College Hospital
2024-03-01
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Series: | Xiehe Yixue Zazhi |
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Online Access: | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0552 |
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author | CUI Quexuan CHE Lu XU Li |
author_facet | CUI Quexuan CHE Lu XU Li |
author_sort | CUI Quexuan |
collection | DOAJ |
description | The baroreceptor reflex is an essential mechanism for the autonomic nervous system in cardiovascular homeostasis and is closely related to pain regulation. Baroreflex sensitivity (BRS) is an indicator for quantitative evaluation of baroreflex reflex function. Pain sensitivity is negatively correlated with BRS, therefore, BRS has potential application prospects in pain risk prediction and therapeutic efficacy assessment. Vagus nerve stimulation, capable of activating the baroreceptor reflex, has been widely used in acute or chronic pain patients in recent years. This article reviews the mechanism and clinical application progress of the baroreceptor reflex in pain regulation, with the hope of providing reference for further exploring treatment to regulate baroreceptor reflex function in pain treatment. |
first_indexed | 2024-04-24T12:48:30Z |
format | Article |
id | doaj.art-f5215bf1c54148648623942965f449c8 |
institution | Directory Open Access Journal |
issn | 1674-9081 |
language | zho |
last_indexed | 2024-04-24T12:48:30Z |
publishDate | 2024-03-01 |
publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
record_format | Article |
series | Xiehe Yixue Zazhi |
spelling | doaj.art-f5215bf1c54148648623942965f449c82024-04-07T00:28:46ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812024-03-0115225826410.12290/xhyxzz.2023-0552Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical ApplicationCUI QuexuanCHE LuXU LiThe baroreceptor reflex is an essential mechanism for the autonomic nervous system in cardiovascular homeostasis and is closely related to pain regulation. Baroreflex sensitivity (BRS) is an indicator for quantitative evaluation of baroreflex reflex function. Pain sensitivity is negatively correlated with BRS, therefore, BRS has potential application prospects in pain risk prediction and therapeutic efficacy assessment. Vagus nerve stimulation, capable of activating the baroreceptor reflex, has been widely used in acute or chronic pain patients in recent years. This article reviews the mechanism and clinical application progress of the baroreceptor reflex in pain regulation, with the hope of providing reference for further exploring treatment to regulate baroreceptor reflex function in pain treatment.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0552baroreceptor reflexautonomic nervepainvagus nerve stimulationbaroreflex sensitivity |
spellingShingle | CUI Quexuan CHE Lu XU Li Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application Xiehe Yixue Zazhi baroreceptor reflex autonomic nerve pain vagus nerve stimulation baroreflex sensitivity |
title | Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application |
title_full | Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application |
title_fullStr | Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application |
title_full_unstemmed | Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application |
title_short | Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application |
title_sort | baroreflex in pain regulation pathogenic mechanism and clinical application |
topic | baroreceptor reflex autonomic nerve pain vagus nerve stimulation baroreflex sensitivity |
url | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0552 |
work_keys_str_mv | AT cuiquexuan baroreflexinpainregulationpathogenicmechanismandclinicalapplication AT chelu baroreflexinpainregulationpathogenicmechanismandclinicalapplication AT xuli baroreflexinpainregulationpathogenicmechanismandclinicalapplication |