Molecular Insights into Binding Mode and Interactions of Structure-Based Virtually Screened Inhibitors for <i>Pseudomonas aeruginosa</i> Multiple Virulence Factor Regulator (MvfR)

Molecular Insights into Binding Mode and Interactions of Structure-Based Virtually Screened Inhibitors for <i>Pseudomonas aeruginosa</i> Multiple Virulence Factor Regulator (MvfR)

Multi-drug resistance (MDR) bacterial pathogens pose a threat to global health and warrant the discovery of new therapeutic molecules, particularly those that can neutralize their virulence and stop the evolution of new resistant mechanisms. The superbug nosocomial pathogen, <i>Pseudomonas aer...

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Bibliographic Details
Main Authors: Raed A. H. Almihyawi, Halah M. H. Al-Hasani, Tabarak Sabah Jassim, Ziyad Tariq Muhseen, Sitong Zhang, Guang Chen
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
<i>Pseudomonas aeruginosa</i>
multiple virulence factor regulator
asinex antibacterial library
comprehensive marine natural products database
M64 control
binding free energies
Online Access:https://www.mdpi.com/1420-3049/26/22/6811

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