Control of Slc7a5 sensitivity by the voltage-sensing domain of Kv1 channels

Many voltage-dependent ion channels are regulated by accessory proteins. We recently reported powerful regulation of Kv1.2 potassium channels by the amino acid transporter Slc7a5. In this study, we report that Kv1.1 channels are also regulated by Slc7a5, albeit with different functional outcomes. In...

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Bibliographic Details
Main Authors: Shawn M Lamothe, Nazlee Sharmin, Grace Silver, Motoyasu Satou, Yubin Hao, Toru Tateno, Victoria A Baronas, Harley T Kurata
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/54916