Analytical Verification Performance of Afirma Genomic Sequencing Classifier in the Diagnosis of Cytologically Indeterminate Thyroid Nodules

Analytical Verification Performance of Afirma Genomic Sequencing Classifier in the Diagnosis of Cytologically Indeterminate Thyroid Nodules

Background: Fine needle aspiration (FNA) cytology, a diagnostic test central to thyroid nodule management, may yield indeterminate results in up to 30% of cases. The Afirma® Genomic Sequencing Classifier (GSC) was developed and clinically validated to utilize genomic material obtained during the FNA...

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Bibliographic Details
Main Authors: Yangyang Hao, Yoonha Choi, Joshua E. Babiarz, Richard T. Kloos, Giulia C. Kennedy, Jing Huang, P. Sean Walsh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Endocrinology
Subjects:
thyroid cancer
RNA-Seq
genomics
analytical verification
molecular diagnostics
lab developed test
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00438/full

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