A long-term ketogenic diet in young and aged rats has dissociable effects on prelimbic cortex and CA3 ensemble activity

A long-term ketogenic diet in young and aged rats has dissociable effects on prelimbic cortex and CA3 ensemble activity

IntroductionAge-related cognitive decline has been linked to distinct patterns of cellular dysfunction in the prelimbic cortex (PL) and the CA3 subregion of the hippocampus. Because higher cognitive functions require both structures, selectively targeting a neurobiological change in one region, at t...

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Bibliographic Details
Main Authors: Abbi R. Hernandez, Maya E. Barrett, Katelyn N. Lubke, Andrew P. Maurer, Sara N. Burke
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
aging
ketosis
Arc
Homer
behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1274624/full

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