Comparison of efficacy of ultrasound-guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy: A randomized controlled trial

Background and Aims: Pectoral nerve (PecS II) block is the latest modality for providing postoperative analgesia after breast surgery. The present study was planned to compare the analgesic efficacy of thoracic paravertebral block (TPVB) and PecS II for postoperative analgesia after modified radical...

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Main Authors: Ashwini Siddeshwara, Geeta Singariya, Manoj Kamal, Kamlesh Kumari, Satyanarayan Seervi, Rakesh Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Saudi Journal of Anaesthesia
Subjects:
Online Access:http://www.saudija.org/article.asp?issn=1658-354X;year=2019;volume=13;issue=4;spage=325;epage=331;aulast=Siddeshwara
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author Ashwini Siddeshwara
Geeta Singariya
Manoj Kamal
Kamlesh Kumari
Satyanarayan Seervi
Rakesh Kumar
author_facet Ashwini Siddeshwara
Geeta Singariya
Manoj Kamal
Kamlesh Kumari
Satyanarayan Seervi
Rakesh Kumar
author_sort Ashwini Siddeshwara
collection DOAJ
description Background and Aims: Pectoral nerve (PecS II) block is the latest modality for providing postoperative analgesia after breast surgery. The present study was planned to compare the analgesic efficacy of thoracic paravertebral block (TPVB) and PecS II for postoperative analgesia after modified radical mastectomy (MRM). Methods: A total of 40 female patients undergoing radical mastectomy were randomly allocated into two groups (n = 20). Group T received ultrasound-guided TPVB, while group P received PecS II block using 0.25% levobupivacaine 24 ml + dexamethasone 1 ml (4 mg) before induction of anesthesia. The primary outcome was duration of analgesia (time to request first analgesic dose), while total rescue analgesic consumption in first 24 h, numeric rating score (NRS), and complication were secondary outcomes. The data were analyzed using IBM SPSS software version 22.0. Results: The duration of analgesia was significantly prolonged in the group P than group T (474.1 ± 84.93 versus 371.5 ± 51.53 min, respectively; P < 0.0001). Postoperative morphine consumed at 24 h was less in the group P than group T (11.25 ± 4.75 and 15.0 ± 4.86 mg, respectively; P = 0.018). NRS at movement and rest were lower in the group P as compared to group T at all time intervals (median 3 versus 4). No block-related complication was recorded in any group. Conclusions: The 0.25% levobupivacaine with dexamethasone 4 mg in PecS II block provided longer duration of analgesia than the TPVB in patients undergoing MRM without any adverse effects.
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spelling doaj.art-f52a4746c84b4b819085b3e99d0b5d072022-12-22T01:41:56ZengWolters Kluwer Medknow PublicationsSaudi Journal of Anaesthesia1658-354X2019-01-0113432533110.4103/sja.SJA_25_19Comparison of efficacy of ultrasound-guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy: A randomized controlled trialAshwini SiddeshwaraGeeta SingariyaManoj KamalKamlesh KumariSatyanarayan SeerviRakesh KumarBackground and Aims: Pectoral nerve (PecS II) block is the latest modality for providing postoperative analgesia after breast surgery. The present study was planned to compare the analgesic efficacy of thoracic paravertebral block (TPVB) and PecS II for postoperative analgesia after modified radical mastectomy (MRM). Methods: A total of 40 female patients undergoing radical mastectomy were randomly allocated into two groups (n = 20). Group T received ultrasound-guided TPVB, while group P received PecS II block using 0.25% levobupivacaine 24 ml + dexamethasone 1 ml (4 mg) before induction of anesthesia. The primary outcome was duration of analgesia (time to request first analgesic dose), while total rescue analgesic consumption in first 24 h, numeric rating score (NRS), and complication were secondary outcomes. The data were analyzed using IBM SPSS software version 22.0. Results: The duration of analgesia was significantly prolonged in the group P than group T (474.1 ± 84.93 versus 371.5 ± 51.53 min, respectively; P < 0.0001). Postoperative morphine consumed at 24 h was less in the group P than group T (11.25 ± 4.75 and 15.0 ± 4.86 mg, respectively; P = 0.018). NRS at movement and rest were lower in the group P as compared to group T at all time intervals (median 3 versus 4). No block-related complication was recorded in any group. Conclusions: The 0.25% levobupivacaine with dexamethasone 4 mg in PecS II block provided longer duration of analgesia than the TPVB in patients undergoing MRM without any adverse effects.http://www.saudija.org/article.asp?issn=1658-354X;year=2019;volume=13;issue=4;spage=325;epage=331;aulast=SiddeshwaraDexamethasone; levobupivacaine; modified radical mastectomy; paravertebral block; pectoral nerve block
spellingShingle Ashwini Siddeshwara
Geeta Singariya
Manoj Kamal
Kamlesh Kumari
Satyanarayan Seervi
Rakesh Kumar
Comparison of efficacy of ultrasound-guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy: A randomized controlled trial
Saudi Journal of Anaesthesia
Dexamethasone; levobupivacaine; modified radical mastectomy; paravertebral block; pectoral nerve block
title Comparison of efficacy of ultrasound-guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy: A randomized controlled trial
title_full Comparison of efficacy of ultrasound-guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy: A randomized controlled trial
title_fullStr Comparison of efficacy of ultrasound-guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy: A randomized controlled trial
title_full_unstemmed Comparison of efficacy of ultrasound-guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy: A randomized controlled trial
title_short Comparison of efficacy of ultrasound-guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy: A randomized controlled trial
title_sort comparison of efficacy of ultrasound guided pectoral nerve block versus thoracic paravertebral block using levobupivacaine and dexamethasone for postoperative analgesia after modified radical mastectomy a randomized controlled trial
topic Dexamethasone; levobupivacaine; modified radical mastectomy; paravertebral block; pectoral nerve block
url http://www.saudija.org/article.asp?issn=1658-354X;year=2019;volume=13;issue=4;spage=325;epage=331;aulast=Siddeshwara
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