Soluble P-Selectin and von Willebrand Factor Rise in Healthy Volunteers Following Non-exertional Ascent to High Altitude

Soluble P-Selectin and von Willebrand Factor Rise in Healthy Volunteers Following Non-exertional Ascent to High Altitude

Reduced oxygen tensions experienced at high altitudes are thought to predispose to thrombosis, yet there are few studies linking hypoxia, platelet activation, and thrombosis. Reports of platelet phenotypes in hypoxia are inconsistent, perhaps due to differing degrees of hypoxia experienced and the d...

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Bibliographic Details
Main Authors: Helena A. Turton, Josephine Pickworth, Gordon G. Paterson, Allan Lawrie, J. Kenneth Baillie, A. A. Roger Thompson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Physiology
Subjects:
altitude
hypoxia
P-selectin
von Willebrand factor
platelet activation
coagulation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.825819/full

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