$Impaired brain fractalkine-CX3CR1 signaling is implicated in cognitive dysfunction in diet-induced obese mice$

Impaired brain fractalkine-CX3CR1 signaling is implicated in cognitive dysfunction in diet-induced obese mice

Introduction A diet high in saturated fat is well known to affect neuronal function and contribute to cognitive decline in experimental animals and humans. Fractalkine released from neurons acts on its receptor, CX3C chemokine receptor 1 (CX3CR1), in the microglia to regulate several brain functions...

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Bibliographic Details
Main Authors:	Namiko Kawamura, Goro Katsuura, Nobuko Yamada-Goto, Ela Novianti, Akio Inui, Akihiro Asakawa
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2021-08-01
Series:	BMJ Open Diabetes Research & Care
Online Access:	https://drc.bmj.com/content/9/1/e001492.full

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