Hyperprogression After Immune-Checkpoint Inhibitor Treatment: Characteristics and Hypotheses

Hyperprogression After Immune-Checkpoint Inhibitor Treatment: Characteristics and Hypotheses

Immunotherapies in tumors have attracted increasing attention. They play an important role in precision medicine. Many immune-checkpoint inhibitors (ICIs) have obtained FDA approval and show good performance in the clinic. Hyperprogressive disease (HPD) after ICIs was first described in November 201...

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Bibliographic Details
Main Authors: Hongjing Zang, Jinwu Peng, Hongmei Zheng, Songqing Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Oncology
Subjects:
ICIs
immunotherapy
HPD
PD-1
PD-L1
CTLA-4
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00515/full

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