The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of hospital: A systematic review and meta-analysis

Aims and objectives: Age increasing is caused physiological changes in the human body, such as reducing the power of the immune system. Weakened immune systems are more susceptible to bacterial infections like tuberculosis. So, this present study was performed for evaluating the prevalence of tuberc...

Full description

Bibliographic Details
Main Authors: M Azami, K Sayehmiri, M H YektaKooshali, M R HafeziAhmadi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:International Journal of Mycobacteriology
Subjects:
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=5;spage=199;epage=200;aulast=Azami
_version_ 1811255815217086464
author M Azami
K Sayehmiri
M H YektaKooshali
M R HafeziAhmadi
author_facet M Azami
K Sayehmiri
M H YektaKooshali
M R HafeziAhmadi
author_sort M Azami
collection DOAJ
description Aims and objectives: Age increasing is caused physiological changes in the human body, such as reducing the power of the immune system. Weakened immune systems are more susceptible to bacterial infections like tuberculosis. So, this present study was performed for evaluating the prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of a hospital. Methods: This systematic review and meta-analysis study has been done based on PRISMA guidelines. A comprehensive search was conducted in Iranian and International databases included: Magiran, Iranmedex, IranDoc, SID, Medlib, Scopus, PubMed, Science Direct, Cochrane, Web of Science, Springer, Wiley Online Library as well as the Google Scholar search engine in the period 1990–2016 by two independent researchers using the Mesh keywords. All of the reviewed studies that had inclusion criterion were been evaluated. The diagnosis of tuberculosis were considered results of physical examination, PPD (Purified Protein Derivative) test, Blood tests, Imaging tests and sputum test. The data were analyzed by using random effects model with the software Stata-Ver.11.1. Results: Five studies with a total number of 2,956 elderly patients were included. The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of the hospital was estimated to be 15% (95%CI: 1–30). The relationship between prevalence of tuberculosis with a year of study was not statistically significant (p = 0.371). Conclusion: This will be the first systematic review of tuberculosis prevalence among elderly patients admitted to the infectious ward in Iran. This study showed a high prevalence of Tuberculosis and it is recommended considering tuberculosis as a differential diagnosis in elderly patients with infectious symptoms.
first_indexed 2024-04-12T17:30:39Z
format Article
id doaj.art-f5393b2b3c5546309d1f8fbfa2ef0f45
institution Directory Open Access Journal
issn 2212-5531
2212-554X
language English
last_indexed 2024-04-12T17:30:39Z
publishDate 2016-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series International Journal of Mycobacteriology
spelling doaj.art-f5393b2b3c5546309d1f8fbfa2ef0f452022-12-22T03:23:09ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2016-01-015519920010.1016/j.ijmyco.2016.11.022The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of hospital: A systematic review and meta-analysisM AzamiK SayehmiriM H YektaKooshaliM R HafeziAhmadiAims and objectives: Age increasing is caused physiological changes in the human body, such as reducing the power of the immune system. Weakened immune systems are more susceptible to bacterial infections like tuberculosis. So, this present study was performed for evaluating the prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of a hospital. Methods: This systematic review and meta-analysis study has been done based on PRISMA guidelines. A comprehensive search was conducted in Iranian and International databases included: Magiran, Iranmedex, IranDoc, SID, Medlib, Scopus, PubMed, Science Direct, Cochrane, Web of Science, Springer, Wiley Online Library as well as the Google Scholar search engine in the period 1990–2016 by two independent researchers using the Mesh keywords. All of the reviewed studies that had inclusion criterion were been evaluated. The diagnosis of tuberculosis were considered results of physical examination, PPD (Purified Protein Derivative) test, Blood tests, Imaging tests and sputum test. The data were analyzed by using random effects model with the software Stata-Ver.11.1. Results: Five studies with a total number of 2,956 elderly patients were included. The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of the hospital was estimated to be 15% (95%CI: 1–30). The relationship between prevalence of tuberculosis with a year of study was not statistically significant (p = 0.371). Conclusion: This will be the first systematic review of tuberculosis prevalence among elderly patients admitted to the infectious ward in Iran. This study showed a high prevalence of Tuberculosis and it is recommended considering tuberculosis as a differential diagnosis in elderly patients with infectious symptoms.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=5;spage=199;epage=200;aulast=AzamiPrevalenceTuberculosisElderlyInfectiousSystematic reviewMeta-analysis
spellingShingle M Azami
K Sayehmiri
M H YektaKooshali
M R HafeziAhmadi
The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of hospital: A systematic review and meta-analysis
International Journal of Mycobacteriology
Prevalence
Tuberculosis
Elderly
Infectious
Systematic review
Meta-analysis
title The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of hospital: A systematic review and meta-analysis
title_full The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of hospital: A systematic review and meta-analysis
title_fullStr The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of hospital: A systematic review and meta-analysis
title_full_unstemmed The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of hospital: A systematic review and meta-analysis
title_short The prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of hospital: A systematic review and meta-analysis
title_sort prevalence of tuberculosis among iranian elderly patients admitted to the infectious ward of hospital a systematic review and meta analysis
topic Prevalence
Tuberculosis
Elderly
Infectious
Systematic review
Meta-analysis
url http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=5;spage=199;epage=200;aulast=Azami
work_keys_str_mv AT mazami theprevalenceoftuberculosisamongiranianelderlypatientsadmittedtotheinfectiouswardofhospitalasystematicreviewandmetaanalysis
AT ksayehmiri theprevalenceoftuberculosisamongiranianelderlypatientsadmittedtotheinfectiouswardofhospitalasystematicreviewandmetaanalysis
AT mhyektakooshali theprevalenceoftuberculosisamongiranianelderlypatientsadmittedtotheinfectiouswardofhospitalasystematicreviewandmetaanalysis
AT mrhafeziahmadi theprevalenceoftuberculosisamongiranianelderlypatientsadmittedtotheinfectiouswardofhospitalasystematicreviewandmetaanalysis
AT mazami prevalenceoftuberculosisamongiranianelderlypatientsadmittedtotheinfectiouswardofhospitalasystematicreviewandmetaanalysis
AT ksayehmiri prevalenceoftuberculosisamongiranianelderlypatientsadmittedtotheinfectiouswardofhospitalasystematicreviewandmetaanalysis
AT mhyektakooshali prevalenceoftuberculosisamongiranianelderlypatientsadmittedtotheinfectiouswardofhospitalasystematicreviewandmetaanalysis
AT mrhafeziahmadi prevalenceoftuberculosisamongiranianelderlypatientsadmittedtotheinfectiouswardofhospitalasystematicreviewandmetaanalysis