Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019
Abstract Background Anorexia nervosa (AN) is a complex and heritable psychiatric disorder, which imposes significant mortality and morbidity on sufferers globally. We aimed to report the prevalence, incidence and disability-adjusted life-years (DALYs) attributable to AN in the Middle East and North...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-12-01
|
| Series: | Journal of Eating Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40337-022-00718-3 |
| _version_ | 1797759765413101568 |
|---|---|
| author | Saeid Safiri Maryam Noori Seyed Aria Nejadghaderi Seyed Ehsan Mousavi Nahid Karamzad Mark J. M. Sullman Stephanie Pirotta Gary S. Collins Morteza Abdollahi Ali-Asghar Kolahi |
| author_facet | Saeid Safiri Maryam Noori Seyed Aria Nejadghaderi Seyed Ehsan Mousavi Nahid Karamzad Mark J. M. Sullman Stephanie Pirotta Gary S. Collins Morteza Abdollahi Ali-Asghar Kolahi |
| author_sort | Saeid Safiri |
| collection | DOAJ |
| description | Abstract Background Anorexia nervosa (AN) is a complex and heritable psychiatric disorder, which imposes significant mortality and morbidity on sufferers globally. We aimed to report the prevalence, incidence and disability-adjusted life-years (DALYs) attributable to AN in the Middle East and North Africa (MENA) region by age, sex and socio-demographic index (SDI), between 1990 and 2019. Methods The disease burden attributable to AN was obtained for the 21 countries located in the MENA region between 1990 and 2019 using publicly available data from the Global Burden of Disease (GBD) 2019 study. All estimates were provided as counts and age-standardized rates per 100,000 population, along with 95% uncertainty intervals (UIs). Results In 2019, the estimated age-standardised point prevalence and incidence rate of AN (per 100,000) in MENA were 49.3 (95% UI: 34.6–70.4) and 16.0 (11.3–22.0), which were 11.4% (7.3–15.4) and 5.9% (2.6–9.1) higher than in 1990, respectively. Furthermore, the regional age-standardised DALY rate was 10.6 (6.3–17.0) per 100,000 in 2019, which was 11.8% (5.2–19.1) higher than in 1990. In 2019, Kuwait [17.3 (10.3-27.9)] and Afghanistan [6.3 (3.7-10.3)] had the highest and lowest age-standardised DALY rates, respectively. In addition, Iran showed the largest increases in the age-standardised point prevalence [30.0% (24.1–36.2)], incidence [24.6% (18.6–30.4)] and DALY [30.5% (22.6–38.9)] rates between 1990 and 2019. In 2019, the number of prevalent cases and prevalence estimates peaked in the 15–19 age group for males and the 20–24 age group for females, with females having a higher number of cases and prevalence in all age groups. In 2019, the age-standardised DALY rates in MENA were higher than the global rates among males aged 10–34 years, but were lower than the global estimates among females in almost all age groups. In addition, the burden of AN was positively associated with the level of socio-economic development during the measurement period. Conclusions The burden of AN in the MENA region increased between 1990 and 2019, which indicates that it is likely to become a more serious public health issue in the future. Up-to-date information about the epidemiological trends in the region would allow health policymakers to make informed and appropriate decisions to help address this issue. Plain English summary The findings of the present study showed that the point prevalence and incidence rate of anorexia nervosa have increased in the Middle East and North Africa region between 1990 and 2019. The highest burden in 2019 was found in Kuwait, while Afghanistan had the lowest attributable burden. In addition, between 1990 and 2019 Iran had the largest increase in the point prevalence of anorexia nervosa. Also in 2019, anorexia nervosa was more prevalent in females and peaked in the 15–19 age group for males and the 20–24 age group for females. Furthermore, as the level of socioeconomic development increased, so did the burden attributable to anorexia nervosa. |
| first_indexed | 2024-03-12T18:49:09Z |
| format | Article |
| id | doaj.art-f53cd057348d49b4a5bf193b04c3867e |
| institution | Directory Open Access Journal |
| issn | 2050-2974 |
| language | English |
| last_indexed | 2024-03-12T18:49:09Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Eating Disorders |
| spelling | doaj.art-f53cd057348d49b4a5bf193b04c3867e2023-08-02T07:26:00ZengBMCJournal of Eating Disorders2050-29742022-12-0110111510.1186/s40337-022-00718-3Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019Saeid Safiri0Maryam Noori1Seyed Aria Nejadghaderi2Seyed Ehsan Mousavi3Nahid Karamzad4Mark J. M. Sullman5Stephanie Pirotta6Gary S. Collins7Morteza Abdollahi8Ali-Asghar Kolahi9Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical SciencesStudent Research Committee, School of Medicine, Iran University of Medical SciencesResearch Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical SciencesStudent Research Committee, Tabriz University of Medical SciencesDepartment of Persian Medicine, School of Traditional Medicine, Tabriz University of Medical SciencesDepartment of Life and Health Sciences, University of NicosiaHealth and Social Care Unit, School of Public Health and Preventive Medicine, Monash UniversityCentre for Statistics in Medicine, Botnar Research Centre, NDORMS, University of OxfordSocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesSocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesAbstract Background Anorexia nervosa (AN) is a complex and heritable psychiatric disorder, which imposes significant mortality and morbidity on sufferers globally. We aimed to report the prevalence, incidence and disability-adjusted life-years (DALYs) attributable to AN in the Middle East and North Africa (MENA) region by age, sex and socio-demographic index (SDI), between 1990 and 2019. Methods The disease burden attributable to AN was obtained for the 21 countries located in the MENA region between 1990 and 2019 using publicly available data from the Global Burden of Disease (GBD) 2019 study. All estimates were provided as counts and age-standardized rates per 100,000 population, along with 95% uncertainty intervals (UIs). Results In 2019, the estimated age-standardised point prevalence and incidence rate of AN (per 100,000) in MENA were 49.3 (95% UI: 34.6–70.4) and 16.0 (11.3–22.0), which were 11.4% (7.3–15.4) and 5.9% (2.6–9.1) higher than in 1990, respectively. Furthermore, the regional age-standardised DALY rate was 10.6 (6.3–17.0) per 100,000 in 2019, which was 11.8% (5.2–19.1) higher than in 1990. In 2019, Kuwait [17.3 (10.3-27.9)] and Afghanistan [6.3 (3.7-10.3)] had the highest and lowest age-standardised DALY rates, respectively. In addition, Iran showed the largest increases in the age-standardised point prevalence [30.0% (24.1–36.2)], incidence [24.6% (18.6–30.4)] and DALY [30.5% (22.6–38.9)] rates between 1990 and 2019. In 2019, the number of prevalent cases and prevalence estimates peaked in the 15–19 age group for males and the 20–24 age group for females, with females having a higher number of cases and prevalence in all age groups. In 2019, the age-standardised DALY rates in MENA were higher than the global rates among males aged 10–34 years, but were lower than the global estimates among females in almost all age groups. In addition, the burden of AN was positively associated with the level of socio-economic development during the measurement period. Conclusions The burden of AN in the MENA region increased between 1990 and 2019, which indicates that it is likely to become a more serious public health issue in the future. Up-to-date information about the epidemiological trends in the region would allow health policymakers to make informed and appropriate decisions to help address this issue. Plain English summary The findings of the present study showed that the point prevalence and incidence rate of anorexia nervosa have increased in the Middle East and North Africa region between 1990 and 2019. The highest burden in 2019 was found in Kuwait, while Afghanistan had the lowest attributable burden. In addition, between 1990 and 2019 Iran had the largest increase in the point prevalence of anorexia nervosa. Also in 2019, anorexia nervosa was more prevalent in females and peaked in the 15–19 age group for males and the 20–24 age group for females. Furthermore, as the level of socioeconomic development increased, so did the burden attributable to anorexia nervosa.https://doi.org/10.1186/s40337-022-00718-3Anorexia nervosaPrevalenceIncidenceEpidemiologyMiddle East and North Africa |
| spellingShingle | Saeid Safiri Maryam Noori Seyed Aria Nejadghaderi Seyed Ehsan Mousavi Nahid Karamzad Mark J. M. Sullman Stephanie Pirotta Gary S. Collins Morteza Abdollahi Ali-Asghar Kolahi Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019 Journal of Eating Disorders Anorexia nervosa Prevalence Incidence Epidemiology Middle East and North Africa |
| title | Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019 |
| title_full | Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019 |
| title_fullStr | Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019 |
| title_full_unstemmed | Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019 |
| title_short | Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019 |
| title_sort | comparison of the burden of anorexia nervosa in the middle east and north africa region between 1990 and 2019 |
| topic | Anorexia nervosa Prevalence Incidence Epidemiology Middle East and North Africa |
| url | https://doi.org/10.1186/s40337-022-00718-3 |
| work_keys_str_mv | AT saeidsafiri comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT maryamnoori comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT seyedarianejadghaderi comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT seyedehsanmousavi comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT nahidkaramzad comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT markjmsullman comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT stephaniepirotta comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT garyscollins comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT mortezaabdollahi comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 AT aliasgharkolahi comparisonoftheburdenofanorexianervosainthemiddleeastandnorthafricaregionbetween1990and2019 |