High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinoma
We report of a 34-year old man with second intracranial relapse of a suprasellar germinoma. Despite of extensive pretreatment with radiation and conventional chemotherapy relapse occurred and was treated with sequential high-dose chemotherapy followed by transfusion of autologous peripheral stem cel...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | deu |
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German Medical Science GMS Publishing House
2003-07-01
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| Series: | GMS German Medical Science |
| Online Access: | http://www.egms.de/en/gms/2003-1/000003.shtml |
| _version_ | 1818514378535731200 |
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| author | Ziske, Carsten Mezger, Jörg Jiménez, Carlos Kleinschmidt, Rolf Pels, Hendrik Schlegel, Uwe Schmidt-Wolf, Ingo G.H. |
| author_facet | Ziske, Carsten Mezger, Jörg Jiménez, Carlos Kleinschmidt, Rolf Pels, Hendrik Schlegel, Uwe Schmidt-Wolf, Ingo G.H. |
| author_sort | Ziske, Carsten |
| collection | DOAJ |
| description | We report of a 34-year old man with second intracranial relapse of a suprasellar germinoma. Despite of extensive pretreatment with radiation and conventional chemotherapy relapse occurred and was treated with sequential high-dose chemotherapy followed by transfusion of autologous peripheral stem cells. The high-dose chemotherapy course was complicated by refractory derailment of pineal gland insufficiency. The patient achieved a complete remission after high dose chemotherapy which lasted for 13 months. Subsequently, he developed a third relapse and died. |
| first_indexed | 2024-12-11T00:14:55Z |
| format | Article |
| id | doaj.art-f53cd1d1b8e24ad2b757bde0edc5edd3 |
| institution | Directory Open Access Journal |
| issn | 1612-3174 |
| language | deu |
| last_indexed | 2024-12-11T00:14:55Z |
| publishDate | 2003-07-01 |
| publisher | German Medical Science GMS Publishing House |
| record_format | Article |
| series | GMS German Medical Science |
| spelling | doaj.art-f53cd1d1b8e24ad2b757bde0edc5edd32022-12-22T01:28:01ZdeuGerman Medical Science GMS Publishing HouseGMS German Medical Science1612-31742003-07-011Doc03High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinomaZiske, CarstenMezger, JörgJiménez, CarlosKleinschmidt, RolfPels, HendrikSchlegel, UweSchmidt-Wolf, Ingo G.H.We report of a 34-year old man with second intracranial relapse of a suprasellar germinoma. Despite of extensive pretreatment with radiation and conventional chemotherapy relapse occurred and was treated with sequential high-dose chemotherapy followed by transfusion of autologous peripheral stem cells. The high-dose chemotherapy course was complicated by refractory derailment of pineal gland insufficiency. The patient achieved a complete remission after high dose chemotherapy which lasted for 13 months. Subsequently, he developed a third relapse and died.http://www.egms.de/en/gms/2003-1/000003.shtml |
| spellingShingle | Ziske, Carsten Mezger, Jörg Jiménez, Carlos Kleinschmidt, Rolf Pels, Hendrik Schlegel, Uwe Schmidt-Wolf, Ingo G.H. High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinoma GMS German Medical Science |
| title | High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinoma |
| title_full | High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinoma |
| title_fullStr | High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinoma |
| title_full_unstemmed | High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinoma |
| title_short | High-dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary AFP-producing intracranial germinoma |
| title_sort | high dose chemotherapy with autologous peripheral blood stem cell support for recurrent primary afp producing intracranial germinoma |
| url | http://www.egms.de/en/gms/2003-1/000003.shtml |
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