Dynamics and Conformations of a Full-Length CRESS-DNA Replicase

Circular Rep-encoding single-stranded DNA (CRESS-DNA) viruses encode for a Replicase (Rep) that is essential for viral replication. Rep is a helicase with three domains: an endonuclease, an oligomeric, and an ATPase domain (ED, OD, and AD). Our recent cryo-EM structure of the porcine circovirus 2 (P...

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Bibliographic Details
Main Authors: Elvira Tarasova, Reza Khayat
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/12/2393