Target Genes of Autism Risk Loci in Brain Frontal Cortex

Target Genes of Autism Risk Loci in Brain Frontal Cortex

Autism spectrum disorder (ASD) is a complex neuropsychiatric disorder. A number of genetic risk loci have been identified for ASD from genome-wide association studies (GWAS); however, their target genes in relevant tissues and cell types remain to be investigated. The frontal cortex is a key region...

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Bibliographic Details
Main Authors: Yan Sun, Xueming Yao, Michael E. March, Xinyi Meng, Junyi Li, Zhi Wei, Patrick M.A. Sleiman, Hakon Hakonarson, Qianghua Xia, Jin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Genetics
Subjects:
autism
brain frontal cortex
DNA methylation
eQTL
GWAS loci
histone modification
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00707/full

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